Early Metacarpal Bone Mineral Density Loss Using Digital X-Ray Radiogrammetry and 3-Tesla Wrist MRI in Established Rheumatoid Arthritis: A Longitudinal One-Year Observational Study

Figure 4

Image shows wrist MRI disease activity at (a) day 1, (b) week 4, (c) week 12, (d) week 24, and (e) week 52 in patient with early disease (disease duration 5 months at baseline). Over the year, there is large amount of BME (RAMRIS scores: 28, 26, 27, 22.5, and 23 at day 1, week 4, week 12, week 24, and week 52). The patient also had rapid loss in RC-BMD at week 12. There is also marked synovitis in the wrist joint with transient improvement at week 4 distal to triquetrum (red circle).

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