Adherence to Methotrexate in Rheumatoid Arthritis: A Danish Nationwide Cohort Study

Table 1

Characteristics of RA patients at the time of first MTX prescription.

Variables	Number
Age (years ± SD)	59.8 ± 14.4
Men	5,221 (28%)
Women	13,482 (72%)
AMI	774 (4%)
Cerebrovascular disease	991 (5%)
Dementia	80 (0.4%)
Complications to T1D	183 (1%)
Complications to T2D	279 (2%)
T1DM	322 (2%)
T2DM	734 (4%)
Hemiplegia	30 (0.2%)
Heart failure	687 (4%)
Peripheral vascular disease	694 (4%)
Chronic lung disease	1,562 (8%)
Leukemia	29 (0.2%)
Lymphoma	99 (0.5%)
Metastases	98 (0.5%)
Mild liver disease	204 (1%)
Moderate to severe liver disease	29 (0.2%)
Kidney disease	328 (2%)
Cancer	476 (3%)
Ulcer	1,207 (7%)
NSAID within the last year	13,415 (72%)
Prednisolone/prednisone within the last year	9,052 (48%)
Ever prior use of prednisolone/prednisone	11,444 (61%)
Ever seen by private practicing rheumatologist	4,497 (24%)
Time from diagnosis to first MTX prescription (years)	0.66 (IQR 0.26–1.80)

T1DM: type 1 diabetes mellitus.
T2DM: type 2 diabetes mellitus.