Evaluating Systemic Toxicity in Rabbits after Acute Ocular Exposure to Irritant Chemicals

Table 3

Biochemical parameter of rabbits treated with ocular irritant chemicals (acute). CPC: cetyl pyridinium chloride, SS: sodium salicylate, IMI: imidazole, ACT: acetaminophen, and NIC: nicotinamide. All values are mean ± SD, .

Parameters	Control	CPC	SS	IMI	ACT	NIC
SGPT (IU/L)	44 ± 3.53	118.65 ± 5.16	79.16 ± 6.81	85.06 ± 23.42	84.9 ± 2.88	84.9 ± 18.80
SGOT (IU/L)	21.3 ± 1.41	19.35 ± 6.15	22.86 ± 7.47	25.06 ± 4.77	20.33 ± 4.12	168.15 ± 19.70
ALP (IU/L)	61 ± 2.82	40 ± 5.65	35.66 ± 26.38	84.33 ± 11.06	54.33 ± 19.50	62.5 ± 19.09
GGT (IU/L)	10.85 ± 0.77	7.5 ± 0.84	5.33 ± 4.16	3.2 ± 2.36	12.26 ± 5.02	1.5 ± 0.56
Uric acid (mg/dL)	2.52 ± 3.06	0.23 ± 0.01	1.03 ± 0.49	2.41 ± 1.91	0.29 ± 0.07	2.21 ± 0.65
Calcium (mg/dL)	13.4 ± 0.14	13.75 ± 0.07	13.8 ± 0.79	14.83 ± 0.41	13.93 ± 1.10	14.2 ± 0.28
Phosphorous (mg/dL)	3.43 ± 0.17	4.32 ± 0.03	4.64 ± 0.80	5.33 ± 0.63	4.65 ± 0.16	5.26 ± 0.12
Chlorides (mmol/L)	104.3 ± 9.33	115.35 ± 1.34	110.7 ± 3.08	116.5 ± 1.47	109.23 ± 2.51	110.45 ± 1.62
Creatinine (mg/dL)	1.22 ± 0.24	1.05 ± 0.01	1.28 ± 0.42	1.09 ± 0.05	1.61 ± 0.82	0.92 ± 0.04