Research Article
Evaluating Systemic Toxicity in Rabbits after Acute Ocular Exposure to Irritant Chemicals
Table 3
Biochemical parameter of rabbits treated with ocular irritant chemicals (acute). CPC: cetyl pyridinium chloride, SS: sodium salicylate, IMI: imidazole, ACT: acetaminophen, and NIC: nicotinamide. All values are mean ± SD,
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| Parameters | Control | CPC | SS | IMI | ACT | NIC |
| SGPT (IU/L) | 44 ± 3.53 | 118.65 ± 5.16 | 79.16 ± 6.81 | 85.06 ± 23.42 | 84.9 ± 2.88 | 84.9 ± 18.80 | SGOT (IU/L) | 21.3 ± 1.41 | 19.35 ± 6.15 | 22.86 ± 7.47 | 25.06 ± 4.77 | 20.33 ± 4.12 | 168.15 ± 19.70 | ALP (IU/L) | 61 ± 2.82 | 40 ± 5.65 | 35.66 ± 26.38 | 84.33 ± 11.06 | 54.33 ± 19.50 | 62.5 ± 19.09 | GGT (IU/L) | 10.85 ± 0.77 | 7.5 ± 0.84 | 5.33 ± 4.16 | 3.2 ± 2.36 | 12.26 ± 5.02 | 1.5 ± 0.56 | Uric acid (mg/dL) | 2.52 ± 3.06 | 0.23 ± 0.01 | 1.03 ± 0.49 | 2.41 ± 1.91 | 0.29 ± 0.07 | 2.21 ± 0.65 | Calcium (mg/dL) | 13.4 ± 0.14 | 13.75 ± 0.07 | 13.8 ± 0.79 | 14.83 ± 0.41 | 13.93 ± 1.10 | 14.2 ± 0.28 | Phosphorous (mg/dL) | 3.43 ± 0.17 | 4.32 ± 0.03 | 4.64 ± 0.80 | 5.33 ± 0.63 | 4.65 ± 0.16 | 5.26 ± 0.12 | Chlorides (mmol/L) | 104.3 ± 9.33 | 115.35 ± 1.34 | 110.7 ± 3.08 | 116.5 ± 1.47 | 109.23 ± 2.51 | 110.45 ± 1.62 | Creatinine (mg/dL) | 1.22 ± 0.24 | 1.05 ± 0.01 | 1.28 ± 0.42 | 1.09 ± 0.05 | 1.61 ± 0.82 | 0.92 ± 0.04 |
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