Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders

<table>Interrelated and interdependent pathways of (1) folate- and betaine-dependent methionine resynthesis from homocysteine utilizing folate-dependent methionine synthase (MS) and betaine-dependent betaine : homocysteine methyltransferase (BHMT); (2) choline-dependent betaine synthesis; (3) phosphtidylethanoloamine methyltransferasse (PEMT) conversion of phosphatidylethanolamine (PE) to phosphatidylcholine (PC); and (4) choline-dependent synthesis of PC and acetylcholine.</table>

Autism Research and Treatment

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Figure 1

Figure 1: Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders 