Potential Role of Selenoenzymes and Antioxidant Metabolism in relation to Autism Etiology and Pathology

Figure 3

Depiction of potential etiologic contributors to disruptions of selenoenzyme physiology that may lead to disruptions of redox control and pathological consequences of autism and ASD. The factors and agents depicted are not all necessarily involved, but increases in predisposing factors along with additive contributions of increased exposures to thio- and selenoreactive electrophiles would be expected to increase the likelihood of progression to pathology.