Associations between Familial Rates of Psychiatric Disorders and De Novo Genetic Mutations in Autism

Table 1

Genetic group demographic characterization.

Number of subjects	DEL		DUP		LGDM		NON
		%		%		%		%
Total	74		62		267		2111
Female	15	20.3%	10	16.1%	48	18.0%	286	13.5%
Male	14	18.9%	52	83.9%	219	82.0%	1825	86.5%
Race
African-American	1	1.4%	0	0.0%	13	4.9%	89	4.2%
Asian	3	4.1%	1	1.6%	16	6.0%	86	4.1%
Native (American or Hawaiian)	0	0.0%	0	0.0%	0	0.0%	5	0.2%
More than one race	5	6.8%	3	4.8%	25	9.4%	155	7.3%
White	60	81.1%	54	87.1%	200	74.9%	1647	78.0%
Not specified/other	5	6.8%	4	6.5%	13	4.9%	129	6.1%
Household income
<$20,000	1	1.4%	3	4.8%	4	1.5%	63	3.0%
$21,000–$35,000	2	2.7%	3	4.8%	13	4.9%	107	5.1%
$36,000–$50,000	8	10.8%	5	8.1%	23	8.6%	173	8.2%
$51,000–$65,000	7	9.5%	8	12.9%	27	10.1%	222	10.5%
$66,000–$80,000	8	10.8%	7	11.3%	37	13.9%	272	12.9%
$81,000–$100,000	11	14.9%	12	19.4%	50	18.7%	346	16.4%
$101,000–$130,000	11	14.9%	7	11.3%	29	10.9%	314	14.9%
$131,000–$160,000	9	12.2%	6	9.7%	27	10.1%	198	9.4%
>$161,000	14	18.9%	8	12.9%	47	17.6%	324	15.3%
Not specified	3	4.1%	3	4.8%	10	3.7%	92	4.4%
Measure	DEL		DUP		LGDM		NON
	Mean	SD	Mean	SD	Mean	SD	Mean	SD
Age	113.67	45.23	103.03	43.52	113.98	44.12	107.34	43.17
Verbal IQ	67.08	34.40	76.83	30.90	74.44	30.12	77.14	31.36
Nonverbal IQ	70.45	32.26	78.39	27.94	78.39	25.10	83.34	26.25
Internalizing problems	59.68	9.88	59.86	9.62	60.39	9.15	60.02	9.66
Externalizing problems	54.67	11.69	58.20	11.58	56.65	11.13	56.48	10.68