Oxidative Stress, Folate Receptor Autoimmunity, and CSF Findings in Severe Infantile Autism

Table 2

The distribution of blocking and binding FRα autoantibodies in 29 children and their parents.

	P−M−	P+M−	P−M+	P+M+	Total number
Child FRab+	12	3	3	3
Child FRab−	5		2	1	8
Total number	17	3	5	4	29

Among 29 autistic children, whose parents have also been tested, 20 had blocking FRα antibodies associated with binding FRα antibodies in only 5 children. Values in parenthesis (mean ± SE: 0.62 ± 0.63) refer to blocking FRα antibody titers in pmoles FRα blocked/ml serum. In 1 child, only FRα antibodies of the binding type were found.