SHANK3 Genotype Mediates Speech and Language Phenotypes in a Nonclinical Population

Table 1

Scales and subscales by sex and genotype.

Scale	Males			Females
	CC (N = 68)	CT (N = 144)	TT (N = 59)	CC (N = 97)	CT (N = 185)	TT (N = 114)
	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
AQ Social Skills	1.81 ± 1.81	2.28 ± 2.05	2.29 ± 2.24	2.45 ± 2.31	2.51 ± 2.19	2.51 ± 2.45
AQ Attention Switching	4.59 ± 2.00	4.94 ± 2.05	5.00 ± 1.70	4.98 ± 2.10	5.04 ± 2.02	4.99 ± 2.11
AQ Attention to Detail	5.53 ± 2.30	5.54 ± 2.12	5.25 ± 1.83	5.44 ± 2.02	5.62 ± 2.23	5.32 ± 2.04
AQ Communication	1.87 ± 1.43	2.41 ± 1.83	2.19 ± 1.78	2.57 ± 1.77	2.45 ± 1.98	2.44 ± 1.78
AQ Imagination	2.57 ± 1.61	2.56 ± 1.62	2.36 ± 1.41	2.16 ± 1.50	2.07 ± 1.49	2.09 ± 1.61
AQ total	16.37 ± 5.01	17.74 ± 5.50	17.08 ± 5.34	17.61 ± 5.36	17.68 ± 5.88	17.35 ± 6.08
SPQ Ideas of Reference	15.99 ± 3.73	16.60 ± 4.48	16.90 ± 3.90	17.41 ± 4.30	17.34 ± 4.18	17.26 ± 4.60
SPQ Constricted Affect	15.63 ± 4.75	15.82 ± 4.92	15.54 ± 4.26	14.68 ± 4.99	14.68 ± 5.01	15.18 ± 5.07
SPQ Eccentric Behavior	12.07 ± 3.93	12.10 ± 3.60	12.07 ± 4.01	12.03 ± 3.81	11.64 ± 3.74	11.75 ± 4.09
SPQ Social Anxiety	11.32 ± 3.93	11.55 ± 3.58	11.47 ± 3.71	11.94 ± 3.99	12.04 ± 4.15	12 ± 4.49
SPQ Magical Thinking	7.50 ± 3.88	7.264 ± 3.44	6.69 ± 2.53	8.36 ± 3.43	8.78 ± 3.72	8.25 ± 3.64
SPQ Odd Speech	12.57 ± 3.08	12.82 ± 2.76	13.76 ± 2.81	13.90 ± 2.93	13.71 ± 2.98	13.48 ± 3.26
SPQ Unusual Perception	10.54 ± 2.74	10.75 ± 2.69	10.54 ± 2.69	10.45 ± 3.00	10.21 ± 2.78	10.14 ± 2.89
SPQ total	85.63 ± 16.14	86.90 ± 15.00	86.98 ± 14.01	88.77 ± 15.43	88.4 ± 16.12	88.06 ± 17.93