SHANK3 Genotype Mediates Speech and Language Phenotypes in a Nonclinical Population

Table 2

Results from 2-way ANOVA on sex and genotype, for the three genotypic models.

Scale	CC versus CT versus TT	(CC + CT) versus TT	(CT + TT) versus CC
	F(5,661),	F(3,663),	F(3,663),
AQ Social Skills	1.21, 0.30	1.28, 0.28	2.02, 0.11
AQ Attention Switching	0.52, 0.76	0.38, 0.77	0.85, 0.46
AQ Attention to Detail	0.45, 0.82	0.60, 0.61	0.04, 0.99
AQ Communication	1.51, 0.19	1.04, 0.37	2.3, 0.076
AQ Imagination	2.57, 0.026	4.21, 0.005821	4.05, 0.0072
AQ total	0.71, 0.62	0.27, 0.85	0.92, 0.43
SPQ Ideas of Reference	1.53, 0.18	2.24, 0.08	2.49, 0.060
SPQ Constricted Affect	1.25, 0.28	2.07, 0.10	1.81, 0.14
SPQ Eccentric Behavior	0.36, 0.88	0.38, 0.77	0.58, 0.63
SPQ Social Anxiety	0.59, 0.71	0.93, 0.43	0.98, 0.40
SPQ Magical Thinking	5.25, 0.000098	8.40, 0.000018	7.86, 0.000037
SPQ Odd Speech	3.27, 0.0063	5.28, 0.0013	3.90, 0.0088
SPQ Unusual Perception	0.89, 0.49	1.24, 0.30	1.39, 0.25
SPQ total	0.50, 0.78	0.72, 0.54	0.82, 0.48

Bonferroni significant results are shown in boldface.