Influence of Bisphosphonate Treatment on Medullary Macrophages and Osteoclasts: An Experimental Study
Figure 8
Microphotographs of osteoclasts stained immunohistochemically for BrdU. (a): dotted line: osteoclasts corresponding to the sham group showing 8 nuclei, none of which were BrdU-positive. (b): osteoclast corresponding to an olpadronate-treated animal showing at least 15 nuclear profiles, 3 of which were BrdU-positive. (c): osteoclast corresponding to an ALN-treated animal showing 2 BrdU-positive nuclei out of more than 25. The bar represents 50 microns.
