The Role of miRNA in Haematological Malignancy

Table 3

Evidence to strengthen association of miRNA with tumourigenesis [75].

1	Widespread deregulation in multiple cancers
2	Gain or loss of miRNA function secondary to deletions, mutation, or amplifications
3	Documentation of tumour suppressor or promoter activity in animal models
4	Verification of cancer-relevant targets in order to identify likely mechanisms through which miRNAs promote oncogenesis