The RAG Model: A New Paradigm for Genetic Risk Stratification in Multiple Myeloma

Table 1

The international staging system for myeloma [2].

Stage	Criteria	Median survival (months)
I	Serum -microglobulin <3.5 mg/L and serum albumin ≥3.5 g/dL	62
II	Neither stage I or III*	44
III	Serum -microglobulin ≥5.5 mg/L	29

There are two categories for stage II: serum -microglobulin <3.5 mg/L but serum albumin <3.5 g/dL; or serum -microglobulin 3.5 to <5.5 mg/L irrespective of the serum albumin level.