The RAG Model: A New Paradigm for Genetic Risk Stratification in Multiple Myeloma

Table 2

The mSMART risk stratification system in active myeloma [6].

High risk	Intermediate risk	Standard risk
FISH	FISH	FISH
del(17p)	t(4;14)	t(4;14)
t(14;16)		t(6;14)
t(14;20)
GEP	Cytogenetic del(13)	All other patients
High-risk signature
	Hypodiploidy
	Plasma cell labelling index ≥3%