Table of Contents
Bone Marrow Research
Volume 2016, Article ID 7062630, 7 pages
Research Article

Awareness, Knowledge, and Acceptance of Haematopoietic Stem Cell Transplantation for Sickle Cell Anaemia in Nigeria

1Department of Haematology and Blood Transfusion, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria
2Department of Haematology and Blood Transfusion, University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria
3Department of Haematology and Blood Transfusion, National Hospital, Abuja, Nigeria
4Department of Haematology and Blood Transfusion, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
5Department of Haematology and Blood Transfusion, Jos University Teaching Hospital, Jos, Nigeria
6Department of Haematology and Immunology, College of Medicine, University of Nigeria, Enugu Campus, Enugu, Nigeria
7Department of Haematology, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria

Received 4 May 2016; Revised 1 July 2016; Accepted 11 August 2016

Academic Editor: Eva C. Guinan

Copyright © 2016 Adewumi Adediran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Sickle cell anaemia (SCA) is an inherited condition whose clinical manifestations arise from the tendency of haemoglobin to polymerize and deform red blood cells into characteristic sickle shape. Allogeneic bone marrow transplantation offers a cure. The aim of this study was to determine the level of awareness, knowledge, and acceptance of this beneficial procedure in Nigeria. Materials and Methods. This multicentre cross-sectional study was conducted in 7 tertiary hospitals in Nigeria in 2015. Approval was obtained from each institution’s research and ethics committee. A pretested structured questionnaire was administered to respondents aged 18 years and above and to the parents or guardians of those below 18 years of age. Results. There were 265 respondents comprising 120 males and 145 females. One hundred and seventy-one (64.5%) respondents were aware of BMT for the treatment of SCA. About 67.8% (116 of 171) of those who were aware believed SCA can be cured with BMT () and 49.7% (85 of 171) of the respondents accepted BMT (). Conclusion. Awareness of BMT in Nigeria is low when compared with reports from developed countries. The knowledge is poor and acceptance is low. With adequate information, improved education, and psychological support, more Nigerians will embrace BMT.