Effect of Alcohol Structure on the Optimum Condition for Novozym 435-Catalyzed Synthesis of Adipate Esters

Table 2

The predictive response equations relating yield of esterification to process parameters.

Ester	Model in terms of coded factors
Di-n-butyl adipate	𝑌=+86.56+5.10𝐴+8.61𝐵+2.60𝐶+9.65𝐷−2.96𝐵^2−2.62𝐷^2
Di-iso-butyl adipate	𝑌=+94.80+2.92𝐴+10.66𝐵+3.00𝐶+12.30𝐷−5.31𝐵^2 −7.74𝐷^2+1.72𝐴𝐷−6.17𝐵𝐷−2.63𝐶𝐷
Di-sec-butyl adipate	𝑌=+90.31+4.83𝐴+9.96𝐵+1.98𝐶+12.93𝐷−3.46𝐵^2 −6.72𝐷^2−4.44𝐵𝐷
Di-tert-butyl adipate	𝑌=+10.75+0.097𝐴−2.38𝐵+5.48𝐶+0.01𝐷+4.00𝐴^2+2.36𝐵^2+0.78𝐷^2−2.21𝐴𝐷−1.16𝐶𝐷

Y is the percent yield; A the temperature; B the time; C the amount of enzyme; D the substrate molar ratio.