Table of Contents
Biotechnology Research International
Volume 2011, Article ID 768673, 5 pages
http://dx.doi.org/10.4061/2011/768673
Research Article

In Vitro Antimicrobial, Antioxidant Activities and Phytochemical Analysis of Canarium patentinervium Miq. from Malaysia

1School of Pharmacy, Faculty of Science, University of Nottingham, Malaysia Campus, JlnBroga, Semenyih, 43500 Selangor, Malaysia
2School of Biomedical Science, Faculty of Science, University of Nottingham, Malaysia Campus, JlnBroga, Semenyih, 43500 Selangor, Malaysia

Received 3 March 2011; Revised 7 April 2011; Accepted 2 May 2011

Academic Editor: Goetz Laible

Copyright © 2011 R. Mogana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Six different extracts of Canarium patentinervium Miq. (Burseraceae) leaves and barks were screened for their phytochemical composition, and antimicrobial and free radical scavenging activities. Among the different extracts tested, the ethanol extract of leaves showed significant antimicrobial and radical scavenging activities. The most susceptible micro-organisms were found to be Gram-positive bacteria (Staphylococcus aureus, methicillin-resistant Staphylococcus aureus or MRSA) and Gram-negative bacteria (Pseudomonas aeruginosa). Phytochemical analysis of the extracts revealed that the antimicrobial and the radical scavenging activities are mainly due to the presence of tannins and flavonoids. The results obtained suggest that Canarium patentinervium Miq. could be exploited in the management of various infectious diseases.