Biotechnology Research International / 2013 / Article / Fig 3

Research Article

Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study

Figure 3

Superimposition of substrate binding regions of intact (red) and 256 E-K mutated (green) GK structures. The distance between the superimposed residues explains the variation in volume and surface area of substrate binding region, which in turn influences the binding affinity with glucose.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.