Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study

Table 1

PDBsum analysis showing the variations in secondary structural conformations of intact and mutated GK structures.

Secondary conformation^a	Intact GK^b	Mutated GK^c
Sheets	3	3
Beta alpha beta unit	1	1
Beta hairpins	5	5
Beta hairpins	5	4
Strands	13	13
Helices	20	22
Helix-helix interactions	24	40
β turns	34	31
γ turn	3	13

^aType of secondary conformation.
^bNumber of respective secondary conformations observed in intact GK.
^cNumber of respective secondary conformations observed in mutated GK.