Optimization of Medium Composition for the Production of Neomycin by Streptomyces fradiae NCIM 2418 in Solid State Fermentation

Table 1

Nutrients and test levels for Plackett-Burman experiment.

Factors	Name	Units	Low level (−1)	High level (+1)
𝑋1	Soluble starch	% w/w	0.5	1.0
𝑋2	Maltose	% w/w	0.5	1.0
𝑋3	Glucose	% w/w	0.5	1.0
𝑋4	Copper sulphate	% w/w	0.5	1.0
𝑋5	Zinc sulphate	% w/w	0.5	1.0
𝑋6	L-asparatic acid	% w/w	0.5	1.0
𝑋7	L-glutamic acid	% w/w	0.5	1.0
𝑋8	L-Histidine	% w/w	0.5	1.0
𝑋9	Sodium Nitrate	% w/w	0.5	1.0
𝑋10	Ammonium chloride	% w/w	0.5	1.0
𝑋11	Ammonium nitrate	% w/w	0.5	1.0