Research Article
Optimization of Medium Composition for the Production of Neomycin by Streptomyces fradiae NCIM 2418 in Solid State Fermentation
Table 3
Coded and actual values of factors in central composite design.
| Factor | Name | Units | Levels | Axial (−2) | Low (−1) | Center (0) | High (+1) | Axial (+2) |
| | Ammonium chloride | % w/w | 1.25 | 1.5 | 1.75 | 2.0 | 2.25 | | Sodium nitrate | % w/w | 1.25 | 1.5 | 1.75 | 2.0 | 2.25 | | L-Histidine | % w/w | 0.125 | 0.25 | 0.375 | 0.50 | 0.625 | | Ammonium nitrate | % w/w | 0.125 | 0.25 | 0.375 | 0.50 | 0.625 |
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