Research Article

Influence of Halide Solutions on Collagen Networks: Measurements of Physical Properties by Atomic Force Microscopy

Table 1

Viscoelastic properties of solvated collagen fibril and collagen molecules.

FibrilYoung’s modulus (GPa)0.43X-ray diffraction (Sasaki and Odajima, 1996a)
Average value 0.90.4–0.5MEMS stretching (Eppell et al., 2006)
0.2–0.5AFM testing (Van Der Rijt et al., 2006)
0.86 ± 0.45MEMS testing (Shen et al., 2008)
0.47 ± 0.41MEMS testing (Shen et al., 2010)
2.89 ± 0.23AFM testing (Svensson et al., 2010a)
1.87–1.94AFM testing (Svensson et al., 2010b)
0.3–1.2Atomisticmodeling (Gautieri et al., 2011)
0.12 ± 0.05MEMS testing (Shen et al., 2011)
Viscosity (GPa-s)0.09–1.63MEMS testing (Shen et al., 2011)
Relaxation time (s)7–102MEMS testing (Shen et al., 2011)

MoleculeYoung’s modulus (GPa)≈9Brillouin light scattering (Harley et al., 1977)
Average value 5.4 GPa≈5.1Brillouin light scattering (Cusack and Miller, 1979)
3–5.1Estimate from persistence length (Hofmann et al., 1984)
2.9 ± 0.1X-ray diffraction (Sasaki and Odajima, 1996b)
0.35–12Optical trap (Sun et al., 2002)
≈7Reactive atomistic modeling (Buehler, 2006)
4.59 ± 0.38Atomistic modeling (Gautieri et al., 2008)
≈4Atomistic modeling (Gautieri et al., 2009a)
4.62 ± 0.41Coarse-grain modeling (Gautieri et al., 2010)
6–16Atomistic creep test [present work]
Viscosity (GPa-s)(3.84 ± 0.38) · 10−9Atomistic creep test [present work]
Relaxation time (s)≈0.5 · 10−9Atomistic creep test [present work]