Intelligent CAD System for Automatic Detection of Mitotic Cells from Breast Cancer Histology Slide Images Based on Teaching-Learning-Based Optimization

Algorithm 1

TLBO algorithm steps.

Implementation steps of TLBO algorithm

Step  1. Definition of size of population and boundary

   of optimal solution

Step  2. Determine the teacher (best solution) and the

   average student’s position.

Step  3.  Update position of any student based on teacher

   due to the following formula

Step  4. Replacing the new population with the old

   population if

Step  5. Update position of any student

   According to interact with each other

   due to following formula

Step  6. Replacing the new population with the

   old population if

Step  7. Exit if maximum iteration is

   performed, else go to Step  2.