Table of Contents
Computational Biology Journal
Volume 2015 (2015), Article ID 427217, 10 pages
http://dx.doi.org/10.1155/2015/427217
Research Article

Structural Differences in KIR3DL1 and LILRB1 Interaction with HLA-B and the Loading Peptide Polymorphisms: In Silico Evidences

1ProxAgen Ltd., 63 Shipchenski Prohod, 1574 Sofia, Bulgaria
2Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica 18, 00133 Rome, Italy
3Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy

Received 24 August 2015; Revised 21 October 2015; Accepted 26 October 2015

Academic Editor: Jinn Moon Yang

Copyright © 2015 Alba Grifoni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In the Supplementary Material more details about KIR3DL1/HLA and LILRB1/HLA interactions are provided. Table S1-S3 show H-bond and amino acid residues involved in the interaction when different alleles’ combinations are evaluated. Figure S1-S2 show the interaction differences in the three LILRB1 haplotypes analyzed and the role of peptide position 1 in LILRB1 interaction.

  1. Supplementary Material