Chemotherapy Research and Practice / 2011 / Article / Tab 1 / Research Article
Activity of Antimicrobial Peptides and Conventional Antibiotics against Superantigen Positive Staphylococcus aureus Isolated from the Patients with Neoplastic and Inflammatory Erythrodermia Table 1 The activity of antimicrobial peptides and conventional antibiotics against S. aureus clinical isolates.
Strain (no. of isolates) and agent MIC (mg/liter) MBC (mg/liter) Range 50% 90% Range 50% 90% Superantigen negative S. aureus (10) Tachyplesin 3 1–4 2 4 2–4 2 4 Lipopeptide 1–8 2 4 2–8 4 8 Protegrin 1 1–4 2 4 2–8 4 8 Temporin A 8–32 8 16 16–64 16 32 Citropin 1.1 8–32 16 32 16–64 16 64 Aurein 1.2 32–128 64 128 64–128 64 128 Uperin 3.6 128–256 128 128 128-128 128 128 Rifampicin 0.25–1 0.25 1 1-2 0.25 1 Tigecycline 0.5–1 0.5 0.5 1-2 1 1 Linezolid 0.5–2 1 1 NT NT NT Vancomycin 0.5–1 1 1 1–4 1 2 Daptomycin 1–4 1 2 1–4 2 2 Ciprofloxacin 0.25–0.5 0.25 0.5 1–8 1 4 Chloramphenicol 2–32 4 32 8–32 8 32 Erythromycin 0.25–64 0.5 0.5 1–4 1 2 Clindamycin 16–64 32 32 64–128 32 64 Superantigen positive S. aureus (14) Tachyplesin 3 1–4 2 4 2–4 2 4 Lipopeptide 1–8 2 4 2–8 4 8 Protegrin 1 1–4 2 4 2–8 4 8 Temporin A 8–32 8 16 16–64 32 64 Citropin 1.1 8–32 16 32 16–64 16 64 Aurein 1.2 32–128 64 128 64–128 64 128 Uperin 3.6 128–256 128 128 128-128 128 128 Rifampicin 0.25–1 0.25 1 0.5–2 1 2 Tigecycline 0.5–1 0.5 0.5 1-2 1 1 Linezolid 0.5–2 1 2 NT NT NT Vancomycin 0.5–2 1 2 1–4 2 4 Daptomycin 1–4 1 2 1–4 2 4 Ciprofloxacin 0.25–128 2 32 2–128 4 64 Chloramphenicol 4–128 8 64 8–128 16 128 Erythromycin 0.25–512 1 256 4–512 8 128 Clindamycin 8–512 64 512 16–512 64 128