Table of Contents
Chemotherapy Research and Practice
Volume 2011, Article ID 843019, 5 pages
http://dx.doi.org/10.1155/2011/843019
Review Article

Neurotoxicity Caused by the Treatment with Platinum Analogues

Oncology Unit, Department of Pathophysiology, Laikon General Hospital, Athens University School of Medicine, 11527 Athens, Greece

Received 10 September 2010; Revised 29 March 2011; Accepted 4 May 2011

Academic Editor: Athanassios Tsakris

Copyright © 2011 Sousana Amptoulach and Nicolas Tsavaris. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [52 citations]

The following is the list of published articles that have cited the current article.

  • Gabriel Wcislo, and Lubomir Bodnar, “Magnesium Salts in a Cancer Patient: Pathobiology and Protective Functions,” Magnesium in Human Health and Disease, pp. 159–180, 2012. View at Publisher · View at Google Scholar
  • Mustafa Gulec, Elif Oral, Onur B. Dursun, Atakan Yucel, Ahmet Hacimuftuoglu, Fatih Akcay, and Halis Suleyman, “Mirtazapine protects against cisplatin-induced oxidative stress and DNA damage in the rat brain,” Psychiatry and Clinical Neurosciences, vol. 67, no. 1, pp. 50–58, 2012. View at Publisher · View at Google Scholar
  • Matthias Kreppel, Sarah Danscheid, Martin Scheer, Jan Christoffer Lüers, Hans Theodor Eich, Joachim E. Zöller, Orlando Guntinas-Lichius, and Dirk Beutner, “Neoadjuvant Chemoradiation in Squamous Cell Carcinoma of the Maxillary Sinus: A 26-Year Experience,” Chemotherapy Research and Practice, vol. 2012, pp. 1–8, 2012. View at Publisher · View at Google Scholar
  • Giuliano Ciarimboli, “Membrane transporters as mediators of Cisplatin effects and side effects.,” Scientifica, vol. 2012, pp. 473829, 2012. View at Publisher · View at Google Scholar
  • Antonio Ruggiero, Giovanna Trombatore, Silvia Triarico, Roberta Arena, Pietro Ferrara, Maria Scalzone, Filomena Pierri, and Riccardo Riccardi, “Platinum compounds in children with cancer,” Anti-Cancer Drugs, vol. 24, no. 10, pp. 1007–1019, 2013. View at Publisher · View at Google Scholar
  • Manuel Diezi, Thierry Buclin, and Thierry Kuntzer, “Toxic and drug-induced peripheral neuropathies: updates on causes, mechanisms and management,” Current Opinion in Neurology, vol. 26, no. 5, pp. 481–488, 2013. View at Publisher · View at Google Scholar
  • Yanyun Zhu, Junlan Yang, Shunchang Jiao, and Tiefeng Ji, “Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors,” World Journal Of Surgical Oncology, vol. 11, 2013. View at Publisher · View at Google Scholar
  • Alixis Van Horn, and Cynthia Harrison, “Neurologic Complications of Cancer and Cancer Therapy,” Clinical Journal Of Oncology Nursing, vol. 17, no. 4, pp. 418–424, 2013. View at Publisher · View at Google Scholar
  • L. S. Clark, D. L. Hertz, S. Roy, H. L. McLeod, A. A. Motsinger-Reif, E. C. Dees, A. Drobish, and L. A. Carey, “CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel,” Annals Of Oncology, vol. 24, no. 6, pp. 1472–1478, 2013. View at Publisher · View at Google Scholar
  • Mohammad Waseem, and Suhel Parvez, “Mitochondrial dysfunction mediated cisplatin induced toxicity: Modulatory role of curcumin,” Food And Chemical Toxicology, vol. 53, pp. 334–342, 2013. View at Publisher · View at Google Scholar
  • Demin Liu, Chunbai He, Andrew Z. Wang, and Wenbin Lin, “Application of liposomal technologies for delivery of platinum analogs in oncology,” International Journal Of Nanomedicine, vol. 8, pp. 3309–3319, 2013. View at Publisher · View at Google Scholar
  • Mark R. Kelley, Yanlin Jiang, Chunlu Guo, April Reed, Hongdi Meng, and Michael R. Vasko, “Role of the DNA Base Excision Repair Protein, APE1 in Cisplatin, Oxaliplatin, or Carboplatin Induced Sensory Neuropathy,” Plos One, vol. 9, no. 9, 2014. View at Publisher · View at Google Scholar
  • Tania E. Schwingel, Caroline P. Klein, Natalia F. Nicoletti, Cristiana L. Dora, Gabriela Hadrich, Cláudia G. Bica, Tiago G. Lopes, Vinicius Duval da Silva, and Fernanda B. Morrone, “Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin-induced hepatotoxicity and neurotoxicity in mice,” Naunyn-Schmiedeberg's Archives of Pharmacology, 2014. View at Publisher · View at Google Scholar
  • Myo Min, Daniel Roos, Elly Keating, Michael Penniment, Scott Carruthers, Lydia Zanchetta, Karen Wong, John Shakeshaft, and Siddhartha Baxi, “External evaluation of the Radiation Therapy Oncology Group brachial plexus contouring protocol: Several issues identified,” Journal of Medical Imaging and Radiation Oncology, vol. 58, no. 3, pp. 360–368, 2014. View at Publisher · View at Google Scholar
  • Keita Mizuno, Toru Kono, Yasuyuki Suzuki, Chika Miyagi, Yuji Omiya, Kanako Miyano, Yoshio Kase, and Yasuhito Uezono, “Goshajinkigan, a Traditional Japanese Medicine, Prevents Oxaliplatin-Induced Acute Peripheral Neuropathy by Suppressing Functional Alteration of TRP Channels in Rat,” Journal of Pharmacological Sciences, vol. 125, no. 1, pp. 91–98, 2014. View at Publisher · View at Google Scholar
  • Senthilvelan Manohar, Samson Jamesdaniel, and Richard Salvi, “Cisplatin Inhibits Hippocampal Cell Proliferation and Alters the Expression of Apoptotic Genes,” Neurotoxicity Research, vol. 25, no. 4, pp. 369–380, 2014. View at Publisher · View at Google Scholar
  • Haydar Ali Erken, Emine Rabia Koç, Haşmet Yazıcı, Arzu Yay, Gözde Özge Önder, and Saim Furkan Sarıcı, “Selenium Partially Prevents Cisplatin-Induced Neurotoxicity: A Preliminary Study,” NeuroToxicology, 2014. View at Publisher · View at Google Scholar
  • M. Koczywas, P. H. Frankel, T. W. Synold, H-J Lenz, J. E. Mortimer, A. B. El-Khoueiry, D. R. Gandara, M. C. Cristea, V. M. Chung, D. Lim, K. L. Reckamp, D. H. Lau, L. A. Doyle, C. Ruel, M. I. Carroll, and E. M. Newman, “Phase I study of the halichondrin B analogue eribulin mesylate in combination with cisplatin in advanced solid tumors,” British Journal Of Cancer, vol. 111, no. 12, pp. 2268–2274, 2014. View at Publisher · View at Google Scholar
  • Chi T. Viet, Dongmin Dang, Stacy Achdjian, Yi Ye, Samuel G. Katz, and Brian L. Schmidt, “Decitabine Rescues Cisplatin Resistance in Head and Neck Squamous Cell Carcinoma,” Plos One, vol. 9, no. 11, 2014. View at Publisher · View at Google Scholar
  • Graziele Fonseca de Sousa, Samarina Rodrigues Wlodarczyk, and Gisele Monteiro, “Carboplatin: molecular mechanisms of action associated with chemoresistance,” Brazilian Journal Of Pharmaceutical Sciences, vol. 50, no. 4, pp. 693–701, 2014. View at Publisher · View at Google Scholar
  • Seyed Kazem Bagherpour Doun, Sohrab Halal Khor, Dardi Qujeq, Hasan Ebrahimi Shahmabadi, Seyed Ebrahim Alavi, Fatemeh Movahedi, and Azim Akbarzadeh, “Effect of sodium chloride on efficiency of cisplatinum dissolved in dimethyl sulfoxide: An in vitro study,” Indian Journal of Clinical Biochemistry, vol. 29, no. 2, pp. 242–245, 2014. View at Publisher · View at Google Scholar
  • Lidia Zueva, Yomarie Rivera, Lilia Kucheryavykh, Serguei N. Skatchkov, Misty J. Eaton, Priscila Sanabria, and Mikhail Inyushin, “Electron Microscopy in Rat Brain Slices Reveals Rapid Accumulation of Cisplatin on Ribosomes and Other Cellular Components Only in Glia,” Chemotherapy Research and Practice, vol. 2014, pp. 1–5, 2014. View at Publisher · View at Google Scholar
  • Yuanyuan Zhu, and Lianming Liao, “Applications of Nanoparticles for Anticancer Drug Delivery: A Review,” Journal Of Nanoscience And Nanotechnology, vol. 15, no. 7, pp. 4753–4773, 2015. View at Publisher · View at Google Scholar
  • Yuanzeng Min, Joseph M. Caster, Michael J. Eblan, and Andrew Z. Wang, “Clinical Translation of Nanomedicine,” Chemical Reviews, pp. 150619062806005, 2015. View at Publisher · View at Google Scholar
  • Ergun Karavelioglu, Mehmet Gazi Boyaci, Nejdet Simsek, Mehmet Akif Sonmez, Rabia Koc, Mustafa Karademir, Mustafa Guven, and Olcay Eser, “Selenium protects cerebral cells by cisplatin induced neurotoxicity,” Acta Cirurgica Brasileira, vol. 30, no. 6, pp. 394–400, 2015. View at Publisher · View at Google Scholar
  • Saliha Harrach, and Giuliano Ciarimboli, “Role of transporters in the distribution of platinum-based drugs,” Frontiers In Pharmacology, vol. 6, 2015. View at Publisher · View at Google Scholar
  • S. Koeppen, “Peripheral neurotoxicity. Preventive dosage modification,” Onkologe, vol. 21, no. 4, pp. 311–+, 2015. View at Publisher · View at Google Scholar
  • Kristian Barlinn, Hans Lehrach, Timo Siepmann, David Braeuer, Ulrich Buntrock, and Norbert Sassim, “Temporary loss of moral behavior in a patient undergoing chemotherapy with cisplatin - breaking bad,” Bmc Psychiatry, vol. 15, 2015. View at Publisher · View at Google Scholar
  • Mohammad Waseem, Monica Bhardwaj, Heena Tabassum, Sheikh Raisuddin, and Suhel Parvez, “Cisplatin hepatotoxicity mediated by mitochondrial stress,” Drug and Chemical Toxicology, pp. 1–8, 2015. View at Publisher · View at Google Scholar
  • Mahino Fatima, Nazura Usmani, Faldha Firdaus, Mohammad Faraz Zafeer, Shafeeque Ahmad, Kafil Akhtar, S. M. Dawar Husain, Mir Hilal Ahmad, Ehraz Anis, and M. Mobarak Hossain, “In vivo induction of antioxidant response and oxidative stress associated with genotoxicity and histopathological alteration in two commercial fish sp,” Comparative Biochemistry And Physiology C-Toxicology & Pharmacology, vol. 176, pp. 17–30, 2015. View at Publisher · View at Google Scholar
  • Barbara Crone, Michael Aschner, Tanja Schwerdtle, Uwe Karst, and Julia Bornhorst, “Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS,” Metallomics, vol. 7, no. 7, pp. 1189–1195, 2015. View at Publisher · View at Google Scholar
  • Rafaela Scalco Ferreira, Neife Aparecida Guinaim dos Santos, Nádia Maria Martins, Laís Silva Fernandes, and Antonio Cardozo dos Santos, “Non-cytotoxic Concentration of Cisplatin Decreases Neuroplasticity-Related Proteins and Neurite Outgrowth Without Affecting the Expression of NGF in PC12 Cells,” Neurochemical Research, 2016. View at Publisher · View at Google Scholar
  • Shohei Yamamoto, Hideki Ono, Kazuhiko Kume, and Masahiro Ohsawa, “Oxaliplatin treatment changes the function of sensory nerves in rats,” Journal Of Pharmacological Sciences, vol. 130, no. 4, pp. 189–193, 2016. View at Publisher · View at Google Scholar
  • D. A. Fennell, Y. Summers, J. Cadranel, T. Benepal, D. C. Christoph, R. Lal, M. Das, F. Maxwell, C. Visseren-Grul, and D. Ferry, “Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer,” Cancer Treatment Reviews, vol. 44, pp. 42–50, 2016. View at Publisher · View at Google Scholar
  • Kevser Erol, Semra Yigitaslan, Cigdem Unel, Bilgin Kaygisiz, and Engin Yildirim, “Evaluation of Cisplatin Neurotoxicity in Cultured Rat Dorsal Root Ganglia via Cytosolic Calcium Accumulation,” Balkan Medical Journal, vol. 33, no. 2, pp. 144–151, 2016. View at Publisher · View at Google Scholar
  • Kang Young Park, Young Sook Park, Yun Hee Park, Hyun Jung Chang, Eun Sol Cho, Seok-Hyun Kim, and Woo Jin Kim, “Delay of the Blink Reflex in Patients Receiving Platinum-Analogue Chemotherapy.,” Annals of rehabilitation medicine, vol. 40, no. 1, pp. 66–73, 2016. View at Publisher · View at Google Scholar
  • Ramin Rezaee, Amir Abbas Momtazi, Alireza Monemi, and Amirhossein Sahebkar, “Curcumin: a potentially powerful tool to reverse cisplatin-induced toxicity,” Pharmacological Research, 2016. View at Publisher · View at Google Scholar
  • Jiri Grim, Alena Ticha, Radomir Hyspler, Martin Valis, and Zdenek Zadak, “Selected Risk Nutritional Factors for Chemotherapy-Induced Polyneuropathy,” Nutrients, vol. 9, no. 6, pp. 535, 2017. View at Publisher · View at Google Scholar
  • Hana Starobova, and Irina Vetter, “Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy,” Frontiers in Molecular Neuroscience, vol. 10, 2017. View at Publisher · View at Google Scholar
  • Ozkan Kanat, Hulya Ertas, and Burcu Caner, “Platinum-induced neurotoxicity: A review of possible mechanisms,” World Journal of Clinical Oncology, vol. 8, no. 4, pp. 329, 2017. View at Publisher · View at Google Scholar
  • Jianru Pan, Lingling Li, Lili Liang, Huocong He, Ying Su, Xiangling Wang, and Shutao Liu, “Cytoprotective Effects of Cell-Permeable Bifunctional Antioxidant Enzyme, GST-TAT-SOD, against Cisplatin-Induced Cell Damage,” Oxidative Medicine and Cellular Longevity, vol. 2017, pp. 1–7, 2017. View at Publisher · View at Google Scholar
  • Rachel M McQuade, Vanesa Stojanovska, Joel C Bornstein, and Kulmira Nurgali, “Parp Inhibition In Platinum-Based Chemotherapy: Chemopotentiation And Neuroprotection,” Pharmacological Research, 2018. View at Publisher · View at Google Scholar
  • Chun-Tang Chiou, Kaw-Chen Wang, Ying-Chen Yang, Chuen-Lin Huang, Sien-Hung Yang, Yao-Haur Kuo, and Nai-Kuei Huang, “Liu Jun Zi Tang—A Potential, Multi-Herbal Complementary Therapy for Chemotherapy-Induced Neurotoxicity,” International Journal of Molecular Sciences, vol. 19, no. 4, pp. 1258, 2018. View at Publisher · View at Google Scholar
  • M. Reig, R. Bosque, M. Font-Bardía, C. Calvis, R. Messeguer, L. Baldomà, J. Badía, D. Velasco, and C. López, “A study of the properties, reactivity and antitumor activity of novel N -methylated-3-thiazolyl or 3-thienyl carbazoles and their Pd(II) and Pt(II) complexes,” Journal of Inorganic Biochemistry, 2018. View at Publisher · View at Google Scholar
  • Ali Valimahomed, Jennifer Zocca, and Amitabh Gulati, “Breast Cancer Pain: A Review of Pathology and Interventional Techniques,” Essentials of Interventional Cancer Pain Management, pp. 63–83, 2018. View at Publisher · View at Google Scholar
  • Anamaria Falcão Pereira, Francisco Fábio Bezerra de Oliveira, Bruno Wesley de Freitas Alves, Karoline Luanne Santos de Menezes, Aline Kelly Viana de Mesquita, Mario Roberto Pontes Lisboa, Kalina Kelma Oliveira de Sousa, and Mariana Lima Vale, “Neurotoxic effect of oxaliplatin: Comparison with its oxalate-free analogue cis-[PtII(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)] (LLC-1402) in mice,” Toxicology and Applied Pharmacology, 2018. View at Publisher · View at Google Scholar
  • Shanlee M Stevens, Collin M McClelland, John E Trusheim, and Michael S Lee, “Carboplatin-associated cranial neuropathy,” Neuro-Ophthalmology, pp. 1–4, 2018. View at Publisher · View at Google Scholar
  • Giacomo Gattoni, and Graziella Bernocchi, “Calcium-Binding Proteins in the Nervous System during Hibernation: Neuroprotective Strategies in Hypometabolic Conditions?,” International Journal of Molecular Sciences, vol. 20, no. 9, pp. 2364, 2019. View at Publisher · View at Google Scholar
  • V. A. Golibrodo, I. D. Treshchalin, A. E. Shchekotikhin, and E. R. Pereverzeva, “Neurotoxic properties of new antitumor agent anthrafuran,” Russian Journal of Biotherapy, vol. 18, no. 1, pp. 75–79, 2019. View at Publisher · View at Google Scholar
  • Sumit Ghosh, “Cisplatin: The First Metal Based Anticancer Drug,” Bioorganic Chemistry, pp. 102925, 2019. View at Publisher · View at Google Scholar
  • G. Artiaga, A. Iglesias-Jiménez, E. Moreno-Gordaliza, M.L. Mena, and M.M. Gómez-Gómez, “Differences in binding kinetics, bond strength and adduct formation between Pt-based drugs and S- or N-donor groups: A comparative study using mass spectrometry techniques,” European Journal of Pharmaceutical Sciences, 2019. View at Publisher · View at Google Scholar
  • Sandra A.S. van den Heuvel, Jonne Doorduin, Monique A Steegers, Ewald M Bronkhorst, Sandra A Radema, Kris C Vissers, Selina E van der Wal, and Nens van Alfen, “Simple surface EMG recording as a noninvasive screening method for the detection of acute oxaliplatin-induced neurotoxicity: a feasibility pilot study,” Neuroscience Letters, 2019. View at Publisher · View at Google Scholar