Preparation and In Vivo Evaluation of Dichloro(1,2-Diaminocyclohexane)platinum(II)-Loaded Core Cross-Linked Polymer Micelles

Figure 6

Light microscopy images of H&E stained kidney, liver, and spleen. Images were taken at a magnification of 200x. Tissue samples were collected at day 13 following i.v. administration of oxaliplatin or DACHPt/cl-micelles at 4 mg/kg body weight. Vehicle control groups received 100 μL of 5% dextrose. Four administrations were given in total with each administration at every fourth day.