Review Article

Alternative Methods to Treat Nausea and Vomiting from Cancer Chemotherapy

Table 3

The effect of adding medicinal plants to conventional therapy on the intensity of nausea and vomiting in cancer patients under chemotherapy.

StudyYearSample sizeDesign/populationMethodOutcome

Zhou et al. [22]201224Lung cancer patients under chemotherapy in various age-gender groupsCase-controlCitrus aurantium extract reduces nausea and vomiting in patients with lung cancer as compared to control group
Pelletier and Ravi [23]201358Women over 20 years of age with ovary cancer receiving chemotherapyCase-controlCitrus aurantium capsule reduces nausea and vomiting in women with ovary cancer receiving chemotherapy as compared to placebo group
Laniyonu et al. [24]201142Cancer patients under chemotherapy in various age-gender groupsCase-controlHypericum perforatum L. reduces nausea and vomiting in patients with lung cancer as compared to control group
Tian et al. [25]201270 Patients under chemotherapy in various age-gender groups Case-controlAchillea millefolium L. reduces CINV by about 23% in test group as compared to placebo group
Steingraber and Alrawi [26]201396Cancer patients under chemotherapy in various age-gender groupsCase-controlZingiber officinale is more effective on reducing CINV as compared to Citrus aurantium, Hypericum perforatum L., and Achillea millefolium L.
Eberhart and Sripramote [28]201143Women with ovary cancer receiving chemotherapy in various age groups Case-controlZingiber officinale is more effective on reducing CINV in delayed phase
Sontakke et al. [29]200350Cancer patients under chemotherapy in various age-gender groupsCase-controlZingiber officinale is more effective on reducing CINV as compared to metoclopramide
Eberhart et al. [30]2003180Women undergoing genital tract laparoscopyClinical trialThe null effect of Zingiber officinale on nausea and vomiting
Nanthakomon and Pongrojpaw [31]200680Cancer patients under chemotherapy in various age-gender groups Case-controlThe effectiveness of Zingiber officinale on nausea and vomiting was reported
Beytz and Ratehanon [32]201267Cancer patients under chemotherapy in various age-gender groups Case-control Zingiber officinale is more effective on reducing CINV as compared to placebo
Levine et al. [33]200873Cancer patients under chemotherapy in various age-gender groups Case-controlZingiber officinale together with protein in the diet reduces delayed nausea and the consumption of antinausea drugs
Kasper and Pierce [34]201152Cancer patients under chemotherapy in various agesCase-controlFurther effectiveness of Zingiber officinale as compared to dimenhydrinate
Ozgoli et al. [35]200980Cancer patients under chemotherapy in various agesCase-controlZingiber officinale is emphasized as a herbal medication for controlling CINV