Table of Contents
Volume 2011, Article ID 306278, 10 pages
Review Article

The Effects of Very-Low-Calorie Diets on HDL: A Review

Centre for Obesity Research and Epidemiology, Robert Gordon University, St. Andrew Street, Aberdeen AB24 3LR, UK

Received 30 August 2010; Accepted 25 November 2010

Academic Editor: Andrew Brown

Copyright © 2011 Catherine Rolland and Iain Broom. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper investigates the effects of very-low-calorie diets (VLCDs) used in the treatment of obesity on high-density lipoprotein (HDL) levels. Although the studies varied widely in their intervention format, duration, and baseline HDL levels, it would appear that HDL levels usually decrease during active weight loss using a VLCD, but these either return to pre-VLCD levels or improve overall during the weight-maintenance phase. More research needs to be done to determine optimal weight-maintenance programmes and the effects of VLCDs in the short term as well as on HDL levels in groups at increased risk of coronary heart disease.