Research Article

Modulation of Lipoprotein Cholesterol Levels in Plasmodium berghei Malarial Infection by Crude Aqueous Extract of Ganoderma lucidum

Table 2

Serum TC, LDL-, HDL-, and VLDL-cholesterol levels in mice Plasmodium berghei infected mice treated with aqueous extract of Ganoderma lucidum.

Treatment groupsTCLDLHDLVLDL

ControlsNormal8.75 ± 0.86a5.29 ± 0.57a1.46 ± 0.01a2.01 ± 0.01a
Infected68.43 ± 5.33b36.56 ± 5.64b16.14 ± 0.01b15.74 ± 0.01b
Aqueous extractAQ10033.76 ± 2.27c21.77 ± 1.47c3.88 ± 0.01c8.10 ± 0.17c
AQ25039.97 ± 1.29c25.58 ± 0.83c4.40 ± 0.01d9.99 ± 0.06d
AQ50063.87 ± 5.03b40.87 ± 3.22b8.33 ± 0.01e14.69 ± 0.01e
Reference drugCQ66.17 ± 4.50b39.86 ± 2.40b10.43 ± 0.01f15.88 ± 0.02b

Results are means ± SEM of eight independent determinations. Values in the same row carrying different superscripts are significant ( ) from each other.
Note. P-CTR: positive control mice; N-CTR: negative control mice; AQ100: infected group treated with 100 mg/kg G. lucidum; AQ250: infected group treated with 250 mg/kg G. lucidum; AQ500: infected mice treated with 500 mg/kg G. lucidum; CQ: infected mice treated with chloroquine.