Research Article

Modulation of Lipoprotein Cholesterol Levels in Plasmodium berghei Malarial Infection by Crude Aqueous Extract of Ganoderma lucidum

Table 3

Liver TC, LDL-, HDL-, and VLDL-cholesterol levels in Plasmodium berghei-infected mice treated with aqueous extract of Ganoderma lucidum.

Treatment groupsTCLDLHDLVLDL

ControlsNormal66.03 ± 6.97a37.51 ± 3.82a12.67 ± 0.01a15.85 ± 0.06a
Infected171.78 ± 8.70b99.25 ± 8.46b31.31 ± 0.01b41.22 ± 0.02b
Aqueous extractAQ100146.42 ± 4.34c93.70 ± 2.78b19.29 ± 0.25c33.68 ± 0.02c
AQ250150.94 ± 9.54b,c96.60 ± 6.10b16.60 ± 0.11d37.74 ± 0.02d
AQ500172.00 ± 8.35b110.08 ± 5.34b22.36 ± 0.01e39.56 ± 0.06e
Reference drugCQ111.56 ± 4.99d71.40 ± 3.19c13.39 ± 0.01f26.78 ± 0.02f

Results are means ± SEM of eight independent determinations. Values in the same row carrying different superscripts are significant ( ) from each other.
Note. P-CTR: positive control mice; N-CTR: negative control mice; AQ100: infected group treated with 100 mg/kg G. lucidum; AQ250: infected group treated with 250 mg/kg G. lucidum; AQ500: infected mice treated with 500 mg/kg G. lucidum; CQ: infected mice treated with chloroquine.