Table 2: Changes in incremental area under the curve (iAUC) for each metabolic parameter after E460F18 loading at 0 and 4 weeks of pitavastatin treatment.

0 week4 weekP

Triglycerides (mg/dL)3885 (2565–6480)2745 (1883–4508)0.007
Remnant-like particle cholesterol (mg/dL) 0.0012
Apolipoprotein E (mg/dL) 0.1333
Glucose (mg/dL) 0.2289
Insulin2342 (1202–3083)2664 (1441–5439)0.093
(mL/minute) 0.7752
Albumin creatinine ratio 0.2424
(mL/minute) 0.9920
Adjusted urinary excretion of uric acid (mg/kg/hour) 0.0442

Values are shown as mean ± standard deviation. : creatinine clearance; : uric acid clearance.
iAUC for triglycerides and insulin are shown as median and interquartile range.