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Cholesterol
Volume 2014, Article ID 582106, 5 pages
http://dx.doi.org/10.1155/2014/582106
Research Article

Effects of Securigera securidaca Extract on Lipolysis and Adipogenesis in Diabetic Rats

1Pharmacological Research Center of Medicinal Plants, School of Medicine, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran
2Neurocognitive Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran
3Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan 7346181746, Iran

Received 30 April 2014; Revised 30 June 2014; Accepted 30 June 2014; Published 3 August 2014

Academic Editor: Patrizia M. Tarugi

Copyright © 2014 Ahmad Ghorbani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. D. Deshpande, M. Harris-Hayes, and M. Schootman, “Epidemiology of diabetes and diabetes-related complications,” Physical Therapy, vol. 88, no. 11, pp. 1254–1264, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Arca, G. Pigna, and C. Favoccia, “Mechanisms of diabetic dyslipidemia: relevance for atherogenesis,” Current Vascular Pharmacology, vol. 10, no. 6, pp. 684–686, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. C. R. Harper and T. A. Jacobson, “Avoiding statin myopathy: understanding key drug interactions,” Clinical Lipidology, vol. 6, no. 6, pp. 665–674, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. M. J. Sorrentino, “An update on statin alternatives and adjuncts,” Clinical Lipidology, vol. 7, no. 6, pp. 721–730, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. M. P. Solano and R. B. Goldberg, “Management of dyslipidemia in diabetes,” Cardiology in Review, vol. 14, no. 3, pp. 125–135, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Ghorbani, “Phytotherapy for diabetic dyslipidemia: evidence from clinical trials,” Clinical Lipidology, vol. 8, no. 3, pp. 311–319, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Ghorbani, “Best herbs for managing diabetes: a review of clinical studies,” Brazilian Journal of Pharmaceutical Sciences, vol. 49, no. 3, pp. 413–422, 2013. View at Google Scholar
  8. I. Ghiasi, M. R. Nikbakht, H. E. Sadeghi, V. Sabzali, S. Sabzali, and M. Shahrani, “The hypoglycemic effects of a hydro-alcoholic extract from Securigera securidaca seeds on induced diabetic in male rats,” Journal of Shahrekord University of Medical Sciences, vol. 8, pp. 68–73, 2007. View at Google Scholar
  9. H. Hosseinzadeh, M. Ramezani, and A. R. Danaei, “Antihyperglycaemic effect and acute toxicity of Securigera Securidaca L. seed extracts in mice,” Phytotherapy Research, vol. 16, no. 8, pp. 745–747, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Porchezhian and S. H. Ansari, “Effect of Securigera securidaca on blood glucose levels of normal and alloxan-induced diabetic rats,” Pharmaceutical Biology, vol. 39, no. 1, pp. 62–64, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Garjani, F. Fathiazad, A. Zakheri et al., “The effect of total extract of Securigera securidaca L. seeds on serum lipid profiles, antioxidant status, and vascular function in hypercholesterolemic rats,” Journal of Ethnopharmacology, vol. 126, no. 3, pp. 525–532, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. Z. Rajaei, M. R. Hadjzadeh, R. Moradi, A. Ghorbani, and A. Saghebi, “Antihyperglycemic and antihyperlipidemic effects of hydroalcoholic extract of Securigera securidaca seeds in streptozotocin-induced diabetic rats,” Advanced Biomedical Research. In press.
  13. A. Ghorbani, G. R. Omrani, M. A. Hadjzadeh, and M. Varedi, “Proinsulin C-peptide inhibits lipolysis in diabetic rat adipose tissue through phosphodiestrase-3B enzyme,” Hormone and Metabolic Research, vol. 45, no. 3, pp. 221–225, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. R. Shafiee-Nick, A. Ghorbani, F. Vafaee Bagheri, and H. Rakhshandeh, “Chronic administration of a combination of six herbs inhibits the progression of hyperglycemia and decreases serum lipids and aspartate amino transferase activity in diabetic rats,” Advances in Pharmacological Sciences, vol. 2012, Article ID 789796, 6 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Ghorbani, G. R. Omrani, M. A. R. Hadjzadeh, and M. Varedi, “Effects of rat C-peptide-II on lipolysis and glucose consumption in cultured rat adipose tissue,” Experimental and Clinical Endocrinology and Diabetes, vol. 119, no. 6, pp. 343–347, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Ghorbani and M. Abedinzade, “Comparison of in vitro and in situ methods for studying lipolysis,” ISRN Endocrinology, vol. 2013, Article ID 205385, 6 pages, 2013. View at Publisher · View at Google Scholar
  17. A. Ghorbani, M. R. Hadjzadeh, Z. Rajaei, and S. B. Zendehbad, “Effects of fenugreek seeds on adipogenesis and lipolysis in normal and diabetic rat,” Pakistan Journal of Biological Sciences, vol. 17, no. 4, pp. 523–528, 2014. View at Google Scholar
  18. A. Ghorbani, S. A. Jalali, and M. Varedi, “Isolation of adipose tissue mesenchymal stem cells without tissue destruction: a non-enzymatic method,” Tissue & Cell, vol. 46, no. 1, pp. 54–58, 2014. View at Publisher · View at Google Scholar
  19. G. Yu, Z. E. Floyd, X. Wu et al., “Adipogenic differentiation of adipose-derived stem cells,” Methods in Molecular Biology, vol. 702, pp. 193–200, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. S. M. Mortazavian, A. Ghorbani, and T. G. Hesari, “Effect of hydro-alcoholic extracts of viola tricolor and its fractions on proliferation of cervix carcinoma cells,” Iranian Journal of Obstetrics, Gynecology and Infertility, vol. 15, no. 22, pp. 9–16, 2012. View at Google Scholar · View at Scopus
  21. M. A. I. R. Hadjzadeh, J. Tavakol Afshari, A. Ghorbani, and M. T. Shakeri, “The effects of aqueous extract of garlic (Allium sativum L.) on laryngeal cancer cells (Hep-2) and L929 cells in vitro,” Journal of Medicinal Plants, vol. 5, no. 18, pp. 41–48, 2006. View at Google Scholar · View at Scopus
  22. P. Arner and D. Langin, “Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance,” Trends in Endocrinology and Metabolism, vol. 25, pp. 255–262, 2014. View at Publisher · View at Google Scholar
  23. E. Fabbrini, B. S. Mohammed, F. Magkos, K. M. Korenblat, B. W. Patterson, and S. Klein, “Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease,” Gastroenterology, vol. 134, no. 2, pp. 424–431, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Lafontan, “Adipose tissue and adipocyte dysregulation,” Diabetes & Metabolism, vol. 40, pp. 16–28, 2014. View at Google Scholar
  25. O. Soehnlein and F. K. Swirski, “Hypercholesterolemia links hematopoiesis with atherosclerosis,” Trends in Endocrinology and Metabolism, vol. 24, no. 3, pp. 129–136, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. E. A. Fisher and H. N. Ginsberg, “Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins,” The Journal of Biological Chemistry, vol. 277, no. 20, pp. 17377–17380, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. S. H. Choi and H. N. Ginsberg, “Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance,” Trends in Endocrinology and Metabolism, vol. 22, no. 9, pp. 353–363, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. V. Large, O. Peroni, D. Letexier, H. Ray, and M. Beylot, “Metabolism of lipids in human white adipocyte,” Diabetes & Metabolism, vol. 30, no. 4, pp. 294–309, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. G. Perilli, C. Saraceni, MN. Daniels, and A. Ahmad, “Diabetic ketoacidosis: a review and update,” in Current Emergency and Hospital Medicine Reports, vol. 1, pp. 10–17, 1, 2013. View at Google Scholar
  30. A. Ghorbani, M. Varedi, M. R. Hadjzadeh, and G. H. Omrani, “Type-1 diabetes induces depot-specific alterations in adipocyte diameter and mass of adipose tissues in the rat,” Experimental and Clinical Endocrinology and Diabetes, vol. 118, no. 7, pp. 442–448, 2010. View at Publisher · View at Google Scholar · View at Scopus