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Cholesterol
Volume 2014, Article ID 821686, 6 pages
http://dx.doi.org/10.1155/2014/821686
Research Article

Association of the Total Cholesterol Content of Erythrocyte Membranes with the Severity of Disease in Stable Coronary Artery Disease

1Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Hezar-Jerib Street, Isfahan 8174673461, Iran
2Isfahan Cardiovascular Research Centre, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan 8187698191, Iran

Received 27 June 2014; Revised 20 September 2014; Accepted 28 September 2014; Published 20 October 2014

Academic Editor: Gordon Ferns

Copyright © 2014 Gholamreza Namazi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. K. Hansson, “Inflammation, atherosclerosis, and coronary artery disease,” The New England Journal of Medicine, vol. 352, no. 16, pp. 1626–1695, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Stocker and J. Keaney, “Role of oxidative modifications in atherosclerosis,” Physiological Reviews, vol. 84, no. 4, pp. 1381–1478, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Libby, M. Aikawa, and U. Schönbeck, “Cholesterol and atherosclerosis,” Biochimica et Biophysica Acta—Molecular and Cell Biology of Lipids, vol. 1529, no. 1–3, pp. 299–309, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. W. E. Hellings, W. Peeters, F. L. Moll, and G. Pasterkamp, “From vulnerable plaque to vulnerable patient: the search for biomarkers of plaque destabilization,” Trends in Cardiovascular Medicine, vol. 17, no. 5, pp. 162–171, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. D. N. Tziakas, G. K. Chalikias, D. Stakos, and H. Boudoulas, “The role of red blood cells in the progression and instability of atherosclerotic plaque,” International Journal of Cardiology, vol. 142, no. 1, pp. 2–7, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. D. N. Tziakas, G. K. Chalikias, D. Stakos et al., “Independent and additive predictive value of total cholesterol content of erythrocyte membranes with regard to coronary artery disease clinical presentation,” International Journal of Cardiology, vol. 150, no. 1, pp. 22–27, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Zhang, L. Pan, Y. Xu et al., “Total cholesterol content of erythrocyte membranes in acute coronary syndrome: correlation with apolipoprotein A-I and lipoprotein (a),” Coronary Artery Disease, vol. 22, no. 3, pp. 145–152, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. K. C. Koskinas and G. D. Giannoglou, “Intraplaque hemorrhage, RBC-derived cholesterol, and plaque progression: time to move from conjecture to evidence?” JACC: Cardiovascular Imaging, vol. 5, no. 11, pp. 1185–1186, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Tziakas, G. Chalikias, A. Grapsa, T. Gioka, I. Tentes, and S. Konstantinides, “Red blood cell distribution width—a strong prognostic marker in cardiovascular disease—is associated with cholesterol content of erythrocyte membrane,” Clinical Hemorheology and Microcirculation, vol. 51, no. 4, pp. 243–254, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. Y. Zhong, H. Tang, Q. Zeng et al., “Total cholesterol content of erythrocyte membranes is associated with the severity of coronary artery disease and the therapeutic effect of rosuvastatin,” Upsala Journal of Medical Sciences, vol. 117, no. 4, pp. 390–398, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Zhang, K. Tu, Y. Xu et al., “Sphingomyelin in erythrocyte membranes increases the total cholesterol content of erythrocyte membranes in patients with acute coronary syndrome,” Coronary Artery Disease, vol. 24, no. 5, pp. 361–367, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Tabas, “Cholesterol and phospholipid metabolism in macrophages,” Biochimica et Biophysica Acta, vol. 1529, no. 1–3, pp. 164–174, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. J. R. Guyton and K. F. Klemp, “Development of the lipid-rich core in human atherosclerosis,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 16, no. 1, pp. 4–11, 1996. View at Publisher · View at Google Scholar · View at Scopus
  14. E. Arbustini, P. Morbini, A. M. D'Armini et al., “Plaque composition in plexogenic and thromboembolic pulmonary hypertension: the critical role of thrombotic material in pultaceous core formation,” Heart, vol. 88, no. 2, pp. 177–182, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. F. D. Kolodgie, H. K. Gold, A. P. Burke et al., “Intraplaque hemorrhage and progression of coronary atheroma,” The New England Journal of Medicine, vol. 349, no. 24, pp. 2316–2325, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. D. N. Tziakas, J. C. Kaski, G. K. Chalikias et al., “Total cholesterol content of erythrocyte membranes is increased in patients with acute coronary syndrome: a new marker of clinical instability?” Journal of the American College of Cardiology, vol. 49, no. 21, pp. 2081–2089, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Virmani, F. D. Kolodgie, A. P. Burke et al., “Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 10, pp. 2054–2061, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Emami Razavi, M. Pourfarzam, M. Ani, and G. A. Naderi, “The associations between high-density lipoprotein mean particle size and its fatty acid composition,” Biomarkers in Medicine, vol. 7, no. 2, pp. 235–245, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Siavash, M. Sadeghi, F. Salarifar, M. Amini, and F. Shojaee-Moradie, “Comparison of body mass index and waist/height ratio in predicting definite coronary artery disease,” Annals of Nutrition and Metabolism, vol. 53, no. 3-4, pp. 162–166, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. V. Chauhan, J. Tsiouris, A. Chauhan, A. M. Sheikh, W. T. Brown, and M. Vaughan, “Increased oxidative stress and decreased activities of Ca2+/Mg2+-ATPase and Na+/K+-ATPase in the red blood cells of the hibernating black bear,” Life Sciences, vol. 71, no. 2, pp. 153–161, 2002. View at Publisher · View at Google Scholar
  21. M. DeLuise and J. S. Flier, “Functionally abnormal Na+-K+ pump in erythrocytes of a morbidly obese patient,” The Journal of Clinical Investigation, vol. 69, no. 1, pp. 38–44, 1982. View at Publisher · View at Google Scholar · View at Scopus
  22. M. A. K. Markwell, S. M. Haas, L. L. Bieber, and N. E. Tolbert, “A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples,” Analytical Biochemistry, vol. 87, no. 1, pp. 206–210, 1978. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Folch, M. Lees, and G. H. Sloane Stanley, “A simple method for the isolation and purification of total lipides from animal tissues,” The Journal of biological chemistry, vol. 226, no. 1, pp. 497–509, 1957. View at Google Scholar · View at Scopus
  24. G. D. Giannoglou, K. C. Koskinas, D. N. Tziakas et al., “Total cholesterol content of erythrocyte membranes and coronary atherosclerosis: an intravascular ultrasound pilot study.,” Angiology, vol. 60, no. 6, pp. 676–682, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. M.-M. Yu, Y. Xu, J.-H. Zhang et al., “Total cholesterol content of erythrocyte membranes levels are associated with the presence of acute coronary syndrome and high sensitivity C-reactive protein,” International Journal of Cardiology, vol. 145, no. 1, pp. 57–58, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. M. H. Gottlieb, “Rates of cholesterol exchange between human erythrocytes and plasma lipoproteins,” Biochimica et Biophysica Acta, vol. 600, no. 2, pp. 530–541, 1980. View at Publisher · View at Google Scholar · View at Scopus
  27. C. J. Fielding and P. E. Fielding, “Intracellular cholesterol transport,” Journal of Lipid Research, vol. 38, no. 8, pp. 1503–1521, 1997. View at Google Scholar · View at Scopus