Association of the Total Cholesterol Content of Erythrocyte Membranes with the Severity of Disease in Stable Coronary Artery Disease
Table 1
Anthropometric, biochemical, and clinical data in CAD patient (-stenosis) and -stenosis group.
-stenosis patients ()
CAD patients (-stenosis) ()
value
Demographic data
Age (years)
55.1 ± 6.2
56.1 ± 6.8
0.363
Men/women ()
42/20
61/21
0.381
Body mass index (kg/m2)
28.1 ± 3.8
28.0 ± 4.6
0.868
Waist hip ratio
0.91 ± 0.05
0.91 ± 0.06
0.868
Systolic pressure (mm Hg)
129 ± 19
133 ± 23
0.244
Diastolic pressure (mm Hg)
87 ± 12
87 ± 15
0.934
Full blood count analysis
Erythrocyte count (×106/L)
5.12 ± 0.44
5.15 ± 0.43
0.688
Haematocrit (%)
44.15 ± 3.86
44.35 ± 3.81
0.760
Hemoglobin (g/dL)
15.21 ± 1.48
15.18 ± 1.47
0.916
MCV
85.40 ± 5.19
84.85 ± 4.65
0.498
RDW
13.4 (13–13.9)
13.5 (13–13.9)
0.526
White blood cell count (×103/L)
6.57 ± 1.62
6.98 ± 2.02
0.199
Risk factors
Hypertension, (%)
41 (66%)
58 (71%)
0.555
Smoking, (%)
13 (21%)
17 (21%)
0.972
History of ACS, (%)
—
27 (33%)
—
History of coronary intervention
CABG, (%)
—
6 (7.3%)
—
PCI, (%)
—
12 (14.6%)
—
Medications
Aspirin, (%)
37 (59.7)
82 (87.8)
<0.001†
Nitrates, (%)
14 (23%)
42 (51%)
<0.001†
Beta-blockers, (%)
25 (41%)
63 (77%)
<0.001†
Clopidogrel, (%)
20 (32%)
47 (57%)
0.003†
Statins, (%)
24 (39%)
65 (79%)
<0.001†
Biochemistry
Fasting blood glucose (mmol/L)
5.05 ± 0.72
5 ± 0.72
0.681
Triglycerides (mmol/L)
1.57 ± 0.56
1.57 ± 0.52
0.969
Total cholesterol (mmol/L)
4.97 ± 0.95
4.46 ± 0.99
0.002*
HDL cholesterol (mmol/L)
1.26 ± 0.23
1.18 ± 0.26
0.072
LDL cholesterol (mmol/L)
2.71 ± 0.67
2.39 ± 0.69
0.005*
hsCRP (mg/L)
1.4 (0.8–3.3)
1.1 (0.6–3.5)
0.322
-stenosis refers to the patients with nonsignificant coronary stenosis (score ≤ 7); -stenosis refers to the patients with significant coronary stenosis (score > 7). Values are expressed as mean ± SD or median and interquartile range for continuous variables, and as number of patients and % for categorical variables. *For independent -test; †for chi-square test. ACE: Angiotensin Converting Enzyme; Ag: Angiotensin; CABG: Coronary Artery Bypass Graft; CAD: Coronary Artery Disease; HDL: High Density Lipoprotein; hsCRP: high-sensitivity C-Reactive Protein; LDL: Low Density Lipoprotein; MCV: Mean Corpuscular Volume; PCI: Percutaneous Coronary Intervention; RDW: Red blood cell Distribution Width.
