Nonselective Mevalonate Kinase Inhibitor as a Novel Class of Antibacterial Agents

Table 1

MIC and MLC of VS with or without glycine or EDTA.

	Vanadyl sulfate (mg/mL)		Vanadyl sulfate + glycine (mg/mL)		Vanadyl sulfate + EDTA (mg/mL)
	MIC	MLC	MIC	MLC	MIC
S. aureus	2	4	2	2	4
E. faecalis	—	—	2	8	—
E. coli	8	8	4	6	4
P. aeruginosa	—	—	2	2	4

Adding glycine or EDTA improved the antibacterial effect of  VS. Data are expressed as average of three assays.