Serum Cholesterol Reduction Efficacy of Biscuits with Added Plant Stanol Ester

Table 5

Change in serum liver function test between control and stanol groups¹.

	ALT			GGT
	Baseline	4 weeks	% change^2	Baseline	4 weeks	% change^2
Total subjects
Control ( = 60)	19.05 ± 15.93	22.28 ± 13.58^a	27.9 ± 40.5	30.68 ± 28.07	35.60 ± 36.03^b	12.1 ± 24.0
Stanol ( = 59)	18.47 ± 9.78	22.54 ± 13.62^a	27.4 ± 57.3	40.32 ± 43.05	47.20 ± 59.23^b	16.3 ± 48.2
Subjects who have normal baseline liver function test
Control (n = 51)	15.00 ± 6.73	18.65 ± 9.66^a	27.4 ± 35.2	21.41 ± 11.10	23.37 ± 12.81^b	9.3 ± 20.7
Stanol ( = 45)	15.86 ± 7.25	20.23 ± 11.58^a	32.1 ± 63.9	24.23 ± 11.58	29.11 ± 23.51^b	15.8 ± 44.9

Values are means ± SD. ALT: L-alanne aminotransferase (normal values of ALT: 5–40 U/L); GGT: gamma-glutamyltransferase (normal values of GGT for Male: 10–71 U/L, Female: 6–42 U/L).
²Percentage change is based on individual data, (4 weeks-baseline)/baseline × 100.
< 0.01, significant change over time comparing to baseline of ALT.
< 0.01, significant change over time comparing to baseline of GGT.