Table of Contents
Chinese Journal of Biology
Volume 2014 (2014), Article ID 672980, 5 pages
http://dx.doi.org/10.1155/2014/672980
Research Article

Significant Differences in the Prevalence of Elevated HbA1c Levels for Type I and Type II Diabetics Attending the Parirenyatwa Diabetic Clinic in Harare, Zimbabwe

1Department of Medical Laboratory Sciences, University of Zimbabwe College of Health Sciences, P.O. Box AV 178, Avondale, Harare, Zimbabwe
2Faculty of Medicine, University of Oslo, P.O. Box 1078, Blinden, 0316 Oslo, Norway

Received 14 October 2013; Accepted 21 November 2013; Published 23 January 2014

Academic Editors: A. Castañeyra-Perdomo, W. Ding, and J. Xie

Copyright © 2014 Kurai Z. Chako et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Diabetics have chronically elevated glucose levels. High levels of glucose result in nonenzymatic formation of glycosylated haemoglobin (HbA1c). Therefore, elevated HbA1c is a good indicator of poorly controlled diabetes. We used the standard HbA1c method to determine glycemic control in diabetics attending a public health facility in Harare, Zimbabwe. Our study sought to assess the prevalence of elevated HbA1c amongst treated diabetics and compare the HbA1c levels by type of diabetes. The cross-sectional study was carried out at one of the main public health centres in Zimbabwe: the Parirenyatwa Group of Hospitals in Harare. Type I and type II diabetics were recruited and had their blood HbA1c levels measured. The standard one tailed proportion z test was used to test the hypothesis at 5% significance level. Combined prevalence of type I and type II diabetics with elevated HbA1c was 27%. There was no significant difference in levels of HbA1c by age and sex. Over half (54%) of Type I diabetics had elevated HbA1c, suggesting poor glycemic control. In contrast only 24% of the Type II diabetics studied had elevated HbA1c. The difference in proportion of Type I and Type II diabetics with elevated HbA1c suggestive of poor glycemic control was significant ( ).