Hepatoprotective Effect of Citrus limon Fruit Extract against Carbofuran Induced Toxicity in Wistar Rats

Table 1

Effect of carbofuran on activities of antioxidative enzymes and AChE in the rat liver tissues as well as amelioration by C. limon fruit extract.

Parameters	Control	20% CF	C. limon	C. limon + 20% CF
GST liver	1735 ± 306.3	1005 ± 112.9	2006 ± 197.9	1488 ± 127.4
SOD liver	21.13 ± 1.98	12.93 ± 2.67	20.92 ± 2.63	17.26 ± 1.93
Catalase liver	5.65 ± 0.85	3.52 ± 0.71	5.43 ± 1.03	4.54 ± 0.84
AChE liver	6.85 ± 0.51	4.23 ± 0.89	7.28 ± 0.40	6.36 ± 0.31

Specific activity of rat liver GST: µmole mL⁻¹ min⁻¹ mg⁻¹ protein; SOD activity: one unit of the enzyme activity has been expressed as 50% inhibition of autooxidation of pyrogallol min⁻¹mg⁻¹; catalase activity: micromoles of H₂O₂ decomposed per min⁻¹mg⁻¹; specific activity of liver AChE = µmole mL⁻¹ min⁻¹ mg⁻¹. Each data set is presented as Mean ± SD. The signs , , and indicate the data significant at < 0.05, , and , respectively, as compared to the control group.