Oncothermia Basic Research at In Vivo Level: The First Results in Japan
Detailed morphological analysis of the tumor samples marked with red rectangle in Figure 5. 6 H after the treatment the tumor cells look intact, but 24 H after the treatment, the large part of the tumor is dead, and the cells are shrunk with picnotic cell nuclei. In the 48 H and 72 H samples definite late morphological signs of apoptotic cell death were observed: extremely high number of apoptotic bodies (marked with red arrow). 120 H after the treatment morphological signs of leukocyte (mostly neutrophils, marked with green arrow) invasion can be visible.