Conference Paper

The History of Hyperthermia Rise and Decline

Table 2

Commercialized nonthermal AEMF technologies in clinical oncology.

TechnologyTrademarkSystemInventorImplementationCompanySince

ElectrohyperthermiaOncothermia (modulated electrohypethermia)EHY2000 EHY3000A Szasz  
(Hungary)
Approved in EU (CE), Russia, ChinaOncoTherm Group (Germany-Hungary)1988

Electroporation electrochemo therapy (ECT)CliniporatorLM Mir  
(France)
Approved in EU (CE)IGEA Srl (Italy)~1980
EndoVeD Soden  
(Ireland)
I/II phase [83]Mercy University Hospital (Ireland)
electro gene therapy (EGT)MedPulsarGA Hofmann DP Rabussay Z Zhang  
(USA) [84]
Approved in EU (CE)Genetronics Biomedical Corp. (USA)~1997
TriGridRM Bernard FDA approved for clinical trials Ichor Medical Systems Inc. (USA)1994

Electric field therapy tumor treatment field (TTF)NovoTTF-100AY Palty  
(Israel)
Approved by FDA [85] after III phase trial [86]NovoCure Ltd. (Israel)2000

Magnetotherapytherapeutic electromagnetic field (TEMF)Wascher RR Williams D Bouldin FE  
(USA) [87]
I-II?EMF Therapeutics Inc. (USA)~2000

Galvanotherapy electro cancer therapy (ECT)ECTplusH/ДApproved in EU (CE)CUTH Meditech GmbH (Germany)2006
NEUFLOSchroeppel EA, Kroll MW  
(USA) [88]
Approved by FDA for researchIonix Medical Inc. (USA)~2000