Table of Contents
Conference Papers in Science
Volume 2014 (2014), Article ID 410545, 4 pages
http://dx.doi.org/10.1155/2014/410545
Conference Paper

The Inhibitory Effect of Resveratrol on Elastin Amyloidogenesis

1Department of Science, University of Basilicata, Via Ateneo Lucano 10, 85100 Potenza, Italy
2Institut Carnot CIRIMAT, UMR CNRS 5085, Université Paul Sabatier, 31062 Toulouse Cedex 4, France

Received 8 November 2013; Accepted 10 March 2014; Published 13 May 2014

Academic Editors: A. Lepedda and J. C. Rodriguez-Cabello

This Conference Paper is based on a presentation given by Brigida Bochicchio at “LIAC Meeting on Vascular Research 2013” held from 18 September 2013 to 21 September 2013 in Alghero, Italy.

Copyright © 2014 Antonietta Pepe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The role of polyphenols in the prevention of degenerative diseases is emerging in the last years. In this report, we will investigate in vitro the inhibitory effect of resveratrol on elastin amyloidogenesis. The effect of resveratrol on molecular structure was investigated by circular dichroism spectroscopy, while the inhibitory effect on self-assembly was evaluated by turbidimetry as a function of temperature and by atomic force microscopy.