Cardiovascular Psychiatry and Neurology / 2009 / Article / Tab 3

Research Article

The Decrease of n-3 Fatty Acid Energy Percentage in an Equicaloric Diet Fed to B6C3Fe Mice for Three Generations Elicits Obesity

Table 3

The effect of long-lasting low n-3 fatty acid diet on mouse liver fatty acid concentrations in total lipid and total phospholipid extracts. The results are expressed as mean SD of 5 measurements per group.

Fatty acids in total lipid and total phospholipid liver extracts ( g / mg tissue)
Total LipidsTotal Phospholipids
Standard n-3Low n-3 FAStandard n-3Low n-3 FA

sum saturates15.2 ± 3.2 18.7 ± 8.12.72 ± 0.71.98 ± 0.6
sum monosats.12.3 ± 7.321.6 ± 11.61.24 ± 0.220.93 ± 0.31
18:2n-65.55 ± 1.140.23 ± 0.221.34 ± 0.490.97 ± 0.36
18:3n-60.088 ± 0.020.39 ± 0.340.020 ± 0.0080.017 ± 0.007
20:2n-60.17 ± 0.0460.66 ± 0.610.041± 0.0180.030 ± 0.015
20:3n-60.70 ± 0.111.16 ± 0.700.17 ± 0.0590.13 ± 0.063
20:4n-65.54 ± 0.386.64 ± 1.01.64 ± 0.551.36 ± 0.61
22:2n-60.13 ± 0.0080.077 ± 0.0650.00 ± 0.00π0.00 ± 0.00π
22:4n-60.18 ± 0.050.68 ± 0.480.033 ± 0.0160.037 ± 0.021
18:3n-30.087 ± 0.0370.068 ± 0.0610.01 ± 0.0040.00 ± 0.00*
20:3n-30.012 ± 0.0070.011 ± 0.0130.002 ± 0.0010.001 ± 0.001
20:5n-30.097 ± 0.0130.027 ± 0.015*0.022 ± 0.00140.00 ± 0.00*
22:5n-30.17 ± 0.040.055 ± 0.025*0.037 ± 0.0170.01 ± 0.004*
22:6n-32.37 ± 0.270.78 ± 0.093*0.73 ± 0.340.24 ± 0.08*
sum n-6ν6.39 ± 0.479.22 ± 2.751.89 ± 0.631.55 ± 0.68
sum n-3ν2.65 ± 0.260.88 ± 0.14*0.80 ± 0.370.25 ± 0.085*
% n-6 HUFA70.7 ± 2.5591.1 ± 1.28*70.3 ± 8.684.7 ± 6.5*

um n-6 and sum n-3 include the critically bioactive 20 and 22 carbon fatty acids only. The n-6 % HUFA is calculated as: (sum n-6)/[(sum n-6)/(sum n-3)]. 100. oncentrations are lower than 0.01. The statistical significance was calculated using an independent samples T-test as described in methods (Sig. 2-tailed: ).

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.