Mood Disorders Are Glial Disorders: Evidence from In Vivo Studies

Figure 3

Effect sizes according to Cohen [28] for clinical (HAMD scores) and serological (serum S100B) treatment effects in major depression [20]. Effect sizes were calculated as changes between admission and discharge relative to standard deviation at admission for the three available studies [20, 29, 30]. Severity of depression was measured with the Hamilton Depression Rating Scale (HAMD).