Research Article
Association of Ultrasonographic Parameters with Subclinical White-Matter Hyperintensities in Hypertensive Patients
Table 5
Accuracy parameters of different cutoffs of ultrasound parameters for prediction of high white matter hyperintensities score (>20).
| Ultrasound parameter | Cutoff | Sens. | Spec. | PPV | NPV | Overall accuracy | Cohen’s | AUC (95% CI) | |
| CCA-Dmean (cm) | | | | | | | | 0.80 (0.67–0.92) | <0.001 | | ≥0.576 | 96% | 46% | 64% | 92% | 71% | 0.423 | | | | ≥0.666 | 65% | 89% | 85% | 72% | 77% | 0.538 | | | | ≥0.705 | 39% | 96% | 91% | 61% | 67% | 0.346 | | |
| CCA-PSV (cm/sec) | | | | | | | | 0.69 (0.54–0.83) | 0.022 | | ≤34.663 | 39% | 92% | 83% | 60% | 65% | 0.308 | | | | ≤38.470 | 62% | 69% | 67% | 65% | 65% | 0.308 | | | | ≤45.315 | 85% | 39% | 58% | 74% | 62% | 0.231 | | |
| ICA-MFV (cm/sec) | | | | | | | | 0.74 (0.60–0.88) | 0.003 | | ≤19.415 | 27% | 100% | 100% | 58% | 64% | 0.269 | | | | ≤27.545 | 77% | 77% | 77% | 77% | 77% | 0.538 | | | | ≤35.990 | 92% | 31% | 57% | 80% | 62% | 0.231 | | |
| MCA-PI | | | | | | | | 0.82 (0.68–0.95) | <0.001 | | ≥1.063 | 100% | 68% | 74% | 100% | 83% | 0.671 | | | | ≥1.183 | 60% | 86% | 80% | 70% | 74% | 0.469 | | | | ≥1.445 | 25% | 91% | 71% | 57% | 60% | 0.164 | | |
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Sens.: sensitivity, spec.: specificity, PPV: positive predictive value, NPV: negative predictive value, AUC: area under the receiver operating characteristic curve, CI: confidence interval.
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