Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats

Figure 1

Effects of curcumin, DMC, and BDMC pre-treatment on muscular coordination, locomotor activity, and neuroprotective effect on apomorphine induced body rotations in rats lesioned by 6-OHDA. Values are in mean ± SEM (𝑛=6). Levels of significance: ^a𝑃≤0.001; ^a+𝑃≤0.01 compared with lesion; ^b𝑃≤0.001; ^b+𝑃≤0.01; ^b++𝑃≤0.05 compared with lesion + curcumin; ^c𝑃≤0.001; ^c++𝑃≤0.05 compared with lesion + DMC.