Table of Contents
Cardiovascular Psychiatry and Neurology
Volume 2013 (2013), Article ID 953672, 5 pages
http://dx.doi.org/10.1155/2013/953672
Clinical Study

Elevated Troponin Level with Negative Outcome Was Found in Ischemic Stroke

Department of Neurology, Istanbul Medeniyet University Medical Faculty, 34720 Istanbul, Turkey

Received 21 April 2013; Revised 1 June 2013; Accepted 2 June 2013

Academic Editor: Koichi Hirata

Copyright © 2013 Buse Hasırcı et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Troponin increment is a highly sensitive and specific marker of myocardial necrosis. The reason of high troponin levels in acute stroke is not clear. The aim of this study was to identify the relationships between cardiac troponin-I (cTnI) level and stroke. Methods. This study recruited 868 patients who were admitted to Istanbul Medeniyet University due to acute ischemic stroke, and the diagnosis was confirmed by diffusion magnetic resonance imaging. The patients with the causes increasing troponin level were excluded from the study. A total of 239 patients were finally included in the study. Clinics were evaluated by the modified Rankin Scale (mRS) and the National Institutes of Health Stroke Scale (NIHSS). Results. Serum level of troponin was higher in ischemic stroke patients with anterior circulation involvement in comparison to posterior involvement or hemorrhagic stroke ( ). Higher troponin levels related to increased stroke scale scores at discharge in ischemic stroke ( ). The level of cTnI was correlated with stroke scale scores at both admission and discharge in posterior stroke patients ( ). Conclusion. cTnI is a highly specific and sensitive marker of myocardial damage, and its elevation was associated with more severe neurological deficits in acute ischemic stroke.