Table of Contents
Cardiovascular Psychiatry and Neurology
Volume 2017, Article ID 5842182, 6 pages
https://doi.org/10.1155/2017/5842182
Review Article

A Review of Neurogenic Stunned Myocardium

1Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA, USA
2Einstein Institute for Heart and Vascular Health, Einstein Medical Center, Philadelphia, PA, USA
3Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA

Correspondence should be addressed to Sylvia Biso; ude.nietsnie@vlysosib

Received 29 April 2017; Accepted 2 July 2017; Published 10 August 2017

Academic Editor: Eugene Nalivaiko

Copyright © 2017 Sylvia Biso et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. S. Go, D. Mozaffarian, and V. L. Roger, “Executive summary: heart disease and stroke statistics—-2013 update: a report from the American Heart Association,” Circulation, vol. 127, no. 1, pp. 143–152, 2013. View at Publisher · View at Google Scholar
  2. H. M. Bramlett and W. D. Dietrich, “Pathophysiology of cerebral ischemia and brain trauma: similarities and differences,” Journal of Cerebral Blood Flow & Metabolism, vol. 24, no. 2, pp. 133–150, 2004. View at Publisher · View at Google Scholar
  3. J. Prosser, L. MacGregor, K. R. Lees, H.-C. Diener, W. Hacke, and S. Davis, “Predictors of early cardiac morbidity and mortality after ischemic stroke,” Stroke, vol. 38, no. 8, pp. 2295–2302, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Kumar, M. H. Selim, and L. R. Caplan, “Medical complications after stroke,” The Lancet Neurology, vol. 9, no. 1, pp. 105–118, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. P. L. Chin, J. Kaminski, and M. Rout, “Myocardial infarction coincident with cerebrovascular accidents in the elderly,” Age and Ageing, vol. 6, no. 1, pp. 29–37, 1977. View at Publisher · View at Google Scholar · View at Scopus
  6. F. L. Silver, J. W. Norris, A. J. Lewis, and V. C. Hachinski, “Early mortality following stroke: a prospective review,” Stroke, vol. 15, no. 3, pp. 492–496, 1984. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Laowattana, S. L. Zeger, J. A. C. Lima, S. N. Goodman, I. S. Wittstein, and S. M. Oppenheimer, “Left insular stroke is associated with adverse cardiac outcome,” Neurology, vol. 66, no. 4, pp. 477–483, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Touzé, O. Varenne, G. Chatellier, S. Peyrard, P. M. Rothwell, and J.-L. Mas, “Risk of myocardial infarction and vascular death after transient ischemic attack and ischemic stroke: a systematic review and meta-analysis,” Stroke, vol. 36, no. 12, pp. 2748–2755, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Nguyen and J. G. Zaroff, “Neurogenic stunned myocardium,” Current Neurology and Neuroscience Reports, vol. 9, no. 6, pp. 486–491, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. C. R. Wira III, E. Rivers, C. Martinez-Capolino et al., “Cardiac complications in acute ischemic stroke,” Western Journal of Emergency Medicine, vol. 12, no. 4, pp. 414–420, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. T.-D. Wang, C.-C. Wu, and Y.-T. Lee, “Myocardial stunning after cerebral infarction,” International Journal of Cardiology, vol. 58, no. 3, pp. 308–311, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Parekh, B. Venkatesh, D. Cross et al., “Cardiac troponin I predicts myocardial dysfunction in aneurysmal subarachnoid hemorrhage,” Journal of the American College of Cardiology, vol. 36, no. 4, pp. 1328–1335, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. N. U. Ko, “Cardiac manifestations of acute neurologic lesions,” in Aminoff’s Neurology and General Medicine, M. J. Aminoff and S. A. Josephson, Eds., pp. 183–198, Elsevier/Academic Press, Amsterdam, The Netherlands, 2014. View at Google Scholar
  14. T. Kono, H. Morita, T. Kuroiwa, H. Onaka, H. Takatsuka, and A. Fujiwara, “Left ventricular wall motion abnormalities in patients with subarachnoid hemorrhage: Neurogenic stunned myocardium,” Journal of the American College of Cardiology, vol. 24, no. 3, pp. 636–640, 1994. View at Publisher · View at Google Scholar · View at Scopus
  15. K. A. Bybee, T. Kara, A. Prasad et al., “Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction,” Annals of Internal Medicine, vol. 141, no. 11, pp. 858–865, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Y-Hassan, “Acute cardiac sympathetic disruption in the pathogenesis of the takotsubo syndrome: A systematic review of the literature to date,” Cardiovascular Revascularization Medicine, vol. 15, no. 1, pp. 35–42, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. C. W. Liang, R. Chen, E. Macri, and N. Naval, “Preadmission beta-blockers are associated with decreased incidence of neurogenic stunned myocardium in aneurysmal subarachnoid hemorrhage,” Journal of Stroke and Cerebrovascular Diseases, vol. 22, no. 5, pp. 601–607, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Guglin and I. Novotorova, “Neurogenic Stunned Myocardium and Takotsubo Cardiomyopathy Are the Same Syndrome: A Pooled Analysis,” Congestive Heart Failure, vol. 17, no. 3, pp. 127–132, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. N. Banki, A. Kopelnik, and M. W. Dae, “Acute neurocardiogenic injury after subarachnoid hemorrhage,” Circulation, vol. 112, no. 21, pp. 3314–3319, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. K. R. Bulsara, M. J. McGirt, L. Liao et al., “Use of the peak troponin value to differentiate myocardial infarction from reversible neurogenic left ventricular dysfunction associated with aneurysmal subarachnoid hemorrhage,” Journal of Neurosurgery, vol. 98, no. 3, pp. 524–528, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Gongora-Rivera, J. Labreuche, A. Jaramillo, P. G. Steg, J.-J. Hauw, and P. Amarenco, “Autopsy prevalence of coronary atherosclerosis in patients with fatal stroke,” Stroke, vol. 38, no. 4, pp. 1203–1210, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. S. M. Oppenheimer, J. X. Wilson, C. Guiraudon, and D. F. Cechetto, “Insular cortex stimulation produces lethal cardiac arrhythmias: a mechanism of sudden death?” Brain Research, vol. 550, no. 1, pp. 115–121, 1991. View at Publisher · View at Google Scholar · View at Scopus
  23. C. L. Jones, J. Ward, and H. D. Critchley, “The neuropsychological impact of insular cortex lesions,” Journal of Neurology, Neurosurgery and Psychiatry, vol. 81, no. 6, pp. 611–618, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. H. Ay, W. J. Koroshetz, T. Benner et al., “Neuroanatomic correlates of stroke-related myocardial injury,” Neurology, vol. 66, no. 9, pp. 1325–1329, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. T. P. Naidich, E. Kang, and G. M. Fatterpekar, “The Insula: Anatomic Study and MR Imaging Display at 1.5 T,” American Journal of Neuroradiology, vol. 25, no. 2, pp. 222–232, 2004. View at Google Scholar
  26. M. Nagai, S. Hoshide, and K. Kario, “The insular cortex and cardiovascular system: a new insight into the brain-heart axis,” Journal of the American Society of Hypertension, vol. 4, no. 4, pp. 174–182, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. Z.-H. Zhang, S. Rashba, and S. M. Oppenheimer, “Insular cortex lesions alter baroreceptor sensitivity in the urethane- anesthetized rat,” Brain Research, vol. 813, no. 1, pp. 73–81, 1998. View at Publisher · View at Google Scholar · View at Scopus
  28. S. M. Oppenheimer, A. Gelb, J. P. Girvin, and V. C. Hachinski, “Cardiovascular effects of human insular cortex stimulation,” Neurology, vol. 42, no. 9, pp. 1727–1732, 1992. View at Publisher · View at Google Scholar · View at Scopus
  29. P. Sörös and V. Hachinski, “Cardiovascular and neurological causes of sudden death after ischaemic stroke,” The Lancet Neurology, vol. 11, no. 2, pp. 179–188, 2012. View at Publisher · View at Google Scholar · View at Scopus
  30. F. Rincon, M. Dhamoon, Y. Moon et al., “Stroke location and association with fatal cardiac outcomes: Northern manhattan study (NOMAS),” Stroke, vol. 39, no. 9, pp. 2425–2431, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. M. A. Samuels, “The brain-heart connection,” Circulation, vol. 116, no. 1, pp. 77–84, 2007. View at Publisher · View at Google Scholar · View at Scopus
  32. J. Min, M. U. Farooq, E. Greenberg et al., “Cardiac dysfunction after left permanent cerebral focal ischemia: The brain and heart connection,” Stroke, vol. 40, no. 7, pp. 2560–2563, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. J. A. Chalela, M. A. Ezzeddine, L. Davis, and S. Warach, “Myocardial injury in acute stroke: A troponin I study,” Neurocritical Care, vol. 1, no. 3, pp. 343–346, 2004. View at Publisher · View at Google Scholar · View at Scopus
  34. A. H. Katsanos, P. Korantzopoulos, G. Tsivgoulis, A. P. Kyritsis, M. Kosmidou, and S. Giannopoulos, “Electrocardiographic abnormalities and cardiac arrhythmias in structural brain lesions,” International Journal of Cardiology, vol. 167, no. 2, pp. 328–334, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. S. Oppenheimer, “Cerebrogenic cardiac arrhythmias: cortical lateralization and clinical significance,” Clinical Autonomic Research, vol. 16, no. 1, pp. 6–11, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. D. S. Goldstein, “The electrocardiogram in stroke: Relationship to pathophysiological type and comparison with prior tracings,” Stroke, vol. 10, no. 3, pp. 253–259, 1979. View at Publisher · View at Google Scholar · View at Scopus
  37. A. Dogan, E. Tunc, M. Ozturk, M. Kerman, and G. Akhan, “Electrocardiographic changes in patients with ischaemic stroke and their prognostic importance,” International Journal of Clinical Practice, vol. 58, no. 5, pp. 436–440, 2004. View at Publisher · View at Google Scholar · View at Scopus
  38. G. Khechinashvili and K. Asplund, “Electrocardiographic changes in patients with acute stroke: a systematic review,” Cerebrovascular Diseases, vol. 14, no. 2, pp. 67–76, 2002. View at Publisher · View at Google Scholar · View at Scopus
  39. A. Lindgren, B. Wohlfart, O. Pahlm, and B. B. Johansson, “Electrocardiographic changes in stroke patients without primary heart disease,” Clinical Physiology, vol. 14, no. 2, pp. 223–231, 1994. View at Publisher · View at Google Scholar · View at Scopus
  40. M. M. McDermott, F. Lefevre, M. Arron, G. J. Martin, and J. Biller, “St segment depression detected by continuous,” Stroke, vol. 25, no. 9, pp. 1820–1824, 1994. View at Publisher · View at Google Scholar · View at Scopus
  41. K. Miah, M. von Arbin, M. Britton, U. de Faire, C. Helmers, and R. Maasing, “Prognosis in acute stroke with special reference to some cardiac factors,” Journal of Chronic Diseases, vol. 36, no. 3, pp. 279–288, 1983. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Miura, K. Tsuchihashi, E. Yoshida, K. Kobayashi, K. Shimamoto, and O. Iimura, “Electrocardiographic Abnormalities in Cerebrovascular Accidents,” Japanese Journal of Medicine, vol. 23, no. 1, pp. 22–26, 1984. View at Publisher · View at Google Scholar · View at Scopus
  43. B. Kallmünzer, L. Breuer, N. Kahl et al., “Serious cardiac arrhythmias after stroke: incidence, time course, and predictors—a systematic, prospective analysis,” Stroke, vol. 43, no. 11, pp. 2892–2897, 2012. View at Publisher · View at Google Scholar · View at Scopus
  44. S. Koppikar, A. Baranchuk, J. C. Guzmán, and C. A. Morillo, “Review: Stroke and ventricular arrhythmias,” International Journal of Cardiology, vol. 168, no. 2, pp. 653–659, 2013. View at Publisher · View at Google Scholar · View at Scopus
  45. T. P. Davis, J. Alexander, and M. Lesch, “Electrocardiographic changes associated with acute cerebrovascular disease: A clinical review,” Progress in Cardiovascular Diseases, vol. 36, no. 3, pp. 245–260, 1993. View at Publisher · View at Google Scholar · View at Scopus
  46. K. W. Faiz, B. Thommessen, G. Einvik, P. H. Brekke, T. Omland, and O. M. Rønning, “Determinants of high sensitivity cardiac troponin T elevation in acute ischemic stroke,” BMC Neurology, vol. 14, no. 1, article no. 96, 2014. View at Publisher · View at Google Scholar · View at Scopus
  47. J. K. Jensen, S. R. Kristensen, S. Bak, D. Atar, P. F. Høilund-Carlsen, and H. Mickley, “Frequency and significance of troponin T elevation in acute ischemic stroke,” The American Journal of Cardiology, vol. 99, no. 1, pp. 108–112, 2007. View at Publisher · View at Google Scholar · View at Scopus
  48. J. F. Scheitz, M. Endres, H.-C. Mochmann, H. J. Audebert, and C. H. Nolte, “Frequency, determinants and outcome of elevated troponin in acute ischemic stroke patients,” International Journal of Cardiology, vol. 157, no. 2, pp. 239–242, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. B. Hasirci, M. Okay, D. Aǧircan, and A. Koçer, “Elevated troponin level with negative outcome was found in ischemic stroke,” Cardiovascular Psychiatry and Neurology, vol. 2013, Article ID 953672, 2013. View at Publisher · View at Google Scholar · View at Scopus
  50. R. Sandhu, W. S. Aronow, A. Rajdev et al., “Relation of cardiac troponin I levels with in-hospital mortality in patients with ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage,” American Journal of Cardiology, vol. 102, no. 5, pp. 632–634, 2008. View at Publisher · View at Google Scholar · View at Scopus
  51. J. Ghali, D. Allison, T. Kleinig et al., “Elevated serum concentrations of troponin T in acute stroke: What do they mean?” Journal of Clinical Neuroscience, vol. 17, no. 1, pp. 69–73, 2010. View at Publisher · View at Google Scholar · View at Scopus
  52. G. Kerr, G. Ray, O. Wu, D. J. Stott, and P. Langhorne, “Elevated troponin after stroke: a systematic review,” Cerebrovascular Diseases, vol. 28, no. 3, pp. 220–226, 2009. View at Publisher · View at Google Scholar · View at Scopus
  53. J. K. Jensen, D. Atar, and H. Mickley, “Mechanism of troponin elevations in patients with acute ischemic stroke,” American Journal of Cardiology, vol. 99, no. 6, pp. 867–870, 2007. View at Publisher · View at Google Scholar · View at Scopus
  54. P. Amarenco, P. C. Lavallee, J. Labreuche, and et al., “Prevalence of coronary atherosclerosis in patients with cerebral infarction,” Stroke, vol. 42, no. 7, pp. 22–29, 2011. View at Google Scholar
  55. D. Calvet, E. Touzé, O. Varenne, J.-L. Sablayrolles, S. Weber, and J.-L. Mas, “Prevalence of asymptomatic coronary artery disease in ischemic stroke patients: The precoris study,” Circulation, vol. 121, no. 14, pp. 1623–1629, 2010. View at Publisher · View at Google Scholar · View at Scopus
  56. R. J. Adams, M. I. Chimowitz, J. S. Alpert et al., “Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: A scientific statement for healthcare professionals from the stroke council and the council on clinical cardiology of the American Heart Association/American Stroke Association,” Circulation, vol. 108, no. 10, pp. 1278–1290, 2003. View at Publisher · View at Google Scholar · View at Scopus
  57. E. A. Amsterdam, N. K. Wenger, R. G. Brindis et al., “2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines,” Journal of the American College of Cardiology, vol. 64, no. 24, pp. e139–e228, 2014. View at Google Scholar