Development of LC Method for the Simultaneous Determination of Antidepressant Drug Combination Melitracen Hydrochloride and Flupentixol Dihydrochloride in their Combined Dosage Form

Table 2

Summary of validation parameters.

Parameters	MEL	FLU
Detection limit (μg/mL)	0.07	0.02
Quantitation limit (μg/mL)	0.2	0.05
Accuracy(%)	99.81–100.77%	99.46–100.12%
Precision (RSD^a,%)
Intraday precision (𝑛=3)	0.14–0.58%	0.11–0.57%
Interday precision (𝑛=3)	0.11–0.76%	0.13–0.42%
Instrument precision (RSD^a)	0.37 %	0.27 %

^aRSD is relative standard deviation and “𝑛” is number of determinations.