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Chromatography Research International
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Chromatography Research International
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2011
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Article
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Tab 4
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Research Article
Development of LC Method for the Simultaneous Determination of Antidepressant Drug Combination Melitracen Hydrochloride and Flupentixol Dihydrochloride in their Combined Dosage Form
Table 4
Data derived from robustness for proposed method.
Parameters
Normal condition
Change in condition
Change in % RSD
MEL
FLU
Flow Rate
1.0 mL/min
0.9 mL/min
0.33
0.21
1.1 mL/min
0.48
0.11
pH
7.3
6.8
0.28
0.13
7.8
0.31
0.18
Mobile phase ratio
90 : 10
95 : 5
0.17
0.13
85 : 15
0.23
0.18